Pathogenetic treatment for neurotrophic keratopathy

Abstract

Introduction. Continuous soft contact lens (SCL) wearing can result in development of neurotrophic keratopathy. Treatment of this pathology is long-term and, in general, symptomatic: tear-substitute, epithelizing, vitaminous, antibacterial, antiinflammatory therapy. Purpose. To improve a correction method for metabolic alterations in corneal tissues in continuous-SCL-wear-associated neurotrophic keratopathy through using transorbital electrophoresis with 1% thiotriazoline. Material and Methods. We developed a method of treatment for neurotrophic keratopathy which includes a 10 day course of daily transorbital electrophoresis with 1% thiotriazoline as a part of complex therapy. We applied for approval of Author's certificate (application No U 201710621 dated 01 November 2017). Results. Clinical cases of treatment of stage 1 neurotrophic keratopathy are reported. Conclusion. The proposed treatment enables in a short term to significantly decrease pathological changes in corneal tissues in stage 1 neurotrophic keratopathy, to increase comfort in the eyes, to prevent severe complications of neurotrophic keratopathy and soft contact lens wearing.