• Development and structure of the discipline “Applied chemistry in medicine” (elective course) at the school of medicine 

  Grekova, A. V.; Grekova, Ia. F.; Gridina, I. R.; Shyrykalova, A. O.; Reda, Abbassi; Kolomiiets, P. V. (2024)

  Along with teaching the natural science and medical principles, it is the author's proposal to create a new subject for electives, “How Applied Chemistry Helps in Medication” to see education level of medical application ...
• Mechanisms of muscle tissue adaptation in response to the influence of low-dose ionizing radiation 

  Stepanov, H. F.; Dubna, Ye. S.; Vastyanov, R. S.; Mokriienko, E. M.; Buriachkivskyi, E. S. (2024)

  Mechanisms of interaction of ionizing radiation with biological objects are a chain of successive physical and physico-chemical changes, which manifest themselves in the form of excitation, primary and secondary ionization ...
• Experimental substantiation of the expediency of using hyperosmolar colloidal solutions for the correction of renal dysfunction in conditions of thermal skin damage 

  Tiron, O. I.; Khomenko, I. P.; Lurin, I. A.; Tertyshny, S. V.; Stepanov, G. F.; Vastyanov, R. S. (2024)

  Objective. To study the effectiveness of hyperosmolar colloidal solutions of lactoprotein with sorbitol and HAES–LX 5% on changes in renal functional activity in the dynamics of thermal skin damage. Materials and methods. ...
• Transient elastography, ultrasound imaging and liver enzymes in diagnosis of cystic fibrosis-related liver disease in children 

  Tsyunchyk, Yu. G.; Shevchenko, I. M.; Tsyunchyk, A. V.; Stepanov, G. F.; Циунчик, Ю. Г.; Шевченко, І. М.; Циунчик, А. В.; Степанов, Г. Ф. (2024)

  Liver disease is responsible for relevant morbidity and mortality in children with cystic fibrosis. We aimed to assess the predictive value of a combination of transient elastography, ultrasound imaging and serum liver ...
• Therapeutic and preventive properties of amaranth seeds 

  Levitsky, A.; Burdo, O.; Velychko, V.; Shumyvoda, Yu.; Selivanska, I.; Lapinska, A.; Левицький, А.; Бурдо, О.; Величко, В.; Шумивода, Ю.; Селіванська, І.; Лапінська, А. (2024)

  Numerous studies conducted over the past decades have proven the high therapeutic efficiency of the squalene hydrocarbon, obtained for the first time as part of shark liver lipids. A significant content of squalene was ...
• Comparative assessment of the effect of consumption of vegetable oils with different fatty acid composition on lipoperoxidation and the development of liver steatosis 

  Levytsky, A.; Velychko, V.; Selivanska, I.; Lapinska, A.; Левицький, А.; Величко, В.; Селіванська, І.; Лапінська, А. (2023)

  Liver steatosis is an extremely common pathological condition caused by the excessive accumulation of fat in this organ, which leads to the activation of lipoperoxidation and, as a result, to the development of steatohepatitis, ...
• Pathophysiological significance of creatinekinase and lactatedehydrogenase in the mechanisms of adaptation of muscle tissue of descendants 

  Stepanov, G. F. (2023)

  Over the past half century, the human population has seen a significant increase in the proportion of individuals exposed to ionizing radiation. One of the urgent problems of radiobiology is the establishment of the ...
• ATPase activity of actomyosin and myosin in different types of muscles of intact and irradiated animals 

  Stepanov, G. F.; Vastyanov, R. S.; Kostina, A. A.; Lazor, N. V. (2023)

  The large-scale use of sources of ionizing radiation and related accidents caused a fundamentally new problem. The body's resistance to the influence of adverse environmental factors and the probability of pathological ...
• Mineralizing activity of periodontal bone tissue of rats with experimental diabetes 

  Levitsky, A. P.; Selivanskaya, I. О.; Tishchenko, T. L.; Stupak, O. P. (2023)

  Background. To determine the effect of diabetes on the state of periodontal bone tissue. Methods. In rats, diabetes mellitus of the first type (DM1) was reproduced with the help of alloxan and diabetes mellitus of the ...
• Hematological changes in descendants of animals irradiated in different doses 

  Stepanov, G. F.; Vastyanov, R. S.; Kostina, A. A.; Mokriienko, E. M.; Lazor, N. V. (2023)

  An urgent problem today is not only the study of changes in the stability of the genome of somatic cells, the clarification of the mechanisms of its destabilization under the influence of a complex of environmental ...
• Peculiarities of the relationship between the terminal site of glycolysis and the initial segment of gluconeogenesis in the myocardium and skeletal muscles of animals irradiated at different doses 

  Stepanov, G. F.; Vastyanov, R. S.; Kostina, А. А.; Mokriienko, E. M. (2023)

  Existing types of muscles differ not only structurally, but also metabolically (direction of energy exchange, choice of biosubstrates, dependence on the action of mediators, hormones, etc.). A number of studies have been ...
• The significance of gene’s polymorphism TNFα (RS1800620) in the development of fibrosis in patients with viral hepatitis of various etiology 

  Bazhora, Y.; Gudz, V.; Mozgova, V.; Usychenko, K.; Shvets, N. (2023)

  Recently it has been established that cytokines are involved in the regulation of the body’s defense reactions in response to a pathogen and form an independent system for regulating homeostasis. The aim of this work is ...
• Experimental background for hormone-vitamin complex using in course of rehabilitation after ionizing radiation 

  Stepanov, G. F.; Vastyanov, R. S. (2023)

  The aim: To determine the efficacy of the original hormone-vitamin complex in terms of biochemical activity enhancement and muscle system functional activity restoration in the irradiated rat’s descendents. Materials ...
• Involvement of intramuscular pathology at the level of the actomyosin junction into the pathogenetic mechanisms of muscle dysfunctionsin the descendents of irradiated rats 

  Stepanov, G. F.; Vastyanov, R. S.; Степанов, Г. Ф.; Вастьянов, Р. С. (2023)

  The purpose of the study was to assess the contractile proteins concentration and the dynamics of ATP-ase activity changes in striated and cardiac muscles of irradiated animals descendents. 130 1-month-old rats were divided ...
• Analysis of sensitization to different groups of pollen allergens and allergic diseases in patients of the southern region of Ukraine 

  Osintseva, V.; Koval, M.; Filonenko, O. (2023)

  Background: Analyze the features of sensitization to different groups of pollen allergens and allergic diseases in patients of Southern region of Ukraine. Method: 46 people, 18–65 y.o., living in the south of Ukraine ...
• Review: proteins c-Myc and Mycnick as potential targets for the melignant melanoma treatment 

  Maryniuk, G. S.; Stepanov, G. F.; Oleynik, K. V.; Selyvanska, I. O.; Tereshchenko, L. O.; Dubna, Y. S. (2023)

  Malignant melanoma is the most aggressive and life-threatening skin cancer with increasing incidences over the past decades. Despite accounting for only 4 % of all skin cancers, melanoma confers 80 % of skin cancer induced ...
• The impact of hormone-vitamin complex on functional activity of the muscle tissue of descendants of irradiated animals 

  Stepanov, G. F.; Vastyanov, R. S.; Tertyshnyi, S. V.; Petruk, L. H. (2023)

  The aim: To determine the hormone-vitamin complex impact on the terminal links of glycolysis, the tricarboxylic acids cycle, and the initial stage of gluconeogenesis in the muscle tissue in descendants of irradiated ...
• Independent work of students as an important stage in the preparation of medical students in bioorganic chemistry major in distance learning 

  Gridina, I.; Grekova, A.; Burdina, I.; Shirykalova, A. (2023)

  Biochemistry is a basic discipline in the training of medical universities’ medical staff. The purpose of the study of this subject is to form students’ knowledge about metabolism as the basis of vital activity of the ...
• Therapeutic and preventive effects of polyfunctional antidisbiotics drugs on the condition of periodontal bone tissue of rats, who have consumed thermoperoxide sunflower oil for a long time 

  Levitsky, A. P.; Markov, A. V.; Selivanskaya, I. A.; Velichko, V. V.; Badiuk, N. S. (2021)

  Aim: to determine the effectiveness of the therapeutic and prophylactic action of various polyfunctional antidisbiotic drags (PFAD) on the state of the periodontal bone tissue of rats treated with thermoperoxide sunflower ...
• Influence of oral phytogels on biochemical indicators of blood serum of rats treated with oral applications of thermoperoxide sunflower oil 

  Levitsky, A. P.; Zubachyk, V. M.; Markov, A. V.; Sloboda, M. T.; Labush, Iu. Z.; Selivanskaya, I. A.; Badiuk, N. S. (2021)

  Aim. It has been established that the consumption of thermoperoxide fats causes the development of pathological processes in the tissues of the oral cavity, intestines and liver. The purpose of this work: to investigate ...

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