Abstract:
This study was aimed to assess the genetic determinants of the breast tumors. There was shown that genetic predisposition to breast cancer is caused by multiple genes, allelic variants which lead to the low risk of the disease, but with a high frequency in the population represented. These genes may act together, providing a multiplier effect. Identification of additional genes of hereditary predisposition to breast cancer and elucidate the role of variants of known genes is an important task, but no less important, and determine the nature of the interaction between genetic determinants.
