Короткий опис (реферат):
Keratoconus (KC) is a degenerative noninflammatory disease of the cornea which is
characterized by structural changes which leads to progressive thinning and bulging
in the central and/or peripheral part of the cornea and is accompanied by irregular
astigmatism and significant vision impairment.
Today, keratoconus treatment is focused on a stage of disease development. At
progressive KC stages (II-III), corneal collagen cross-linking is performed. At
the present, a latest-generation unit (UV-X™2000, Avedro) is used to perform
accelerated cross-linking, which allows for a threefold decrease of the procedure
duration (to 10 minutes) compared to the standard protocol
Material and Methods. Corneal collagen cross-linking was performed in 71 patients
(100 eyes).
Results. Accelerated corneal collagen cross-linking for keratoconus stages II-III
made it possible to stabilize the pathological process in 100% of cases, based on
12 month follow-up. Keratoconus stabilization was accompanied by: a decrease of
astigmatism by 1.4 D and of the corneal refractive power by 3.2D; an increase of the
corneal thickness by 8.8 nm; an increase of UCVA and BCVA in 96.5% and 89.6%
of cases, respectively; and recovery of normal corneal architectonics according to
confocal biomicroscopy data. Subjectively, 64 patients (90%) noted the improvement
in the vision quality and better tolerance to spectacles correction.
