Видання іноземною мовою. Кафедра фізіології, патологічної фізіології, медичної фізики та інформатики: Recent submissions

Now showing items 121-140 of 307

Pentylenetetrazole-induced kindling as a model metabolic syndrome

Bidnyuk, V. K.; Pervak, M. P.; Poshyvak, O. B.; Yehorenko, O. S.; Varava, S. V.; Godlevsky, L. S.; Haustov, O. O. (2022)

Data on the relationship between epilepsy and metabolic syndrome justified the evaluation of MS markers expression in PTZ-kindled rats. PTZ kindling was induced in four months aged male Wistar rats with three weeks ...
The synergy of Antiepileptic action of Rapamycin, Pioglitazone, and Minocycline on acute seizures in mice

Prybolovets, K. O.; Pervak, M. P.; Al-Nadawi, N.; Liashenko, A. V.; Poshyvak, O. B.; Godlevsky, L. S. (2022)

One-third of patients with epilepsy are resistant to antiepileptic drugs (AED). Combined treatment with neuromodulators with antiserizure action, which are not classical AED, is promising for searching for more effective ...
The synergy of antiepileptic action of combined usage of neuro-vascular modulators with a wide spectrum of effects upon neuronal tissue

Poshyvak, O. B.; Pinyazhko, O. R.; Abumutair, Sh. N.; Pervak, M. P.; Yehorenko, O. S.; Godlevsky, L. S. (2022)

Today, about 70 million people worldwide suffer from epilepsy. In Ukraine, the prevalence of epilepsy is about 2.5 - 4.5 per 1000. Despite the emergence of new, more effective antiepileptic drugs (AEDs), 30% of patients ...
Enhancement of the anticonvulsant effect of the h3 histamine receptor blocker thioperamid against the use of pioglitazone

Yehorenko, O. S.; Pervak, M. P.; Poshyvak, O. B.; Liashenko, A. V.; Godlevsky, L. S. (2022)

The purpose of the study was to study the dynamics of foci of epileptic activity, which were reproduced in the cerebral cortex of kindled rats using the sodium salt of benzylpenicillin, under the conditions of individual ...
The influence of immunodeficiency on the level of CD34-positive cells in the cervix

Gargin, V.; Volokhova, H.; Koshelnyk, O.; Gulbs, O.; Kachailo, I.; Lytvynenko, M. (2022)

There are many studies on changes in cervix, however, there are no data about property of cervical tissue to keep potential for regeneration under influence of immunodeficiency, which is very important since it allows ...
Contemporary approach to online education at the medical school applying Socratic seminar or Socratic circle to lecturing

Shumilina, K. S.; Kornienko, S. M.; Lapshin, D. Ye.; Vastyanov, R. S. (2022)

We have sought the answer to a problem of online education introduced by COVID-19 pandemic. We suppose online education is to be the most dynamic form of professional learning which takes place at a distance with the use ...
Cognitive impairment restoration in patients suffered with stroke during the post-COVID period

Stoyanov, O. M.; Son, A. S.; Vastyanov, R. S.; Turchin, N. I.; Gruzevsky, O. A.; Yermuraki, P. P.; Dzygal, O. F.; Vastyanov, M. R. (2022)

Frequency of vascular complications, including strokes, in patients suffered from COVID-19 infection is known to be increased up to 8 times, especially compared with influenza. The purpose: to investigate the fundamental ...
Experimental background of thermometry using with diagnostic purposes in soft tissue gunshot damages

Khomenko, I. P.; Tertyshnyi, S. V.; Vastyanov, R. S.; Talalayev, K. O.; Turchin, M. I.; Panasenko, S. I.; Хоменко, І. П.; Тертишний, С. В.; Вастьянов, Р. С.; Талалаєв, К. О.; Турчин, М. І.; Панасенко, С. І. (2022)

The problem of treatment of gunshot wounds remains to be one of the most pressing and unresolved issues of modern surgery. Gunshot wounds diagnosis is currently ineffective. There is a need to improve the content and scope ...
Analysis of the relationship between the activity of inducible nitric oxide synthase and interleukin-1 in the pathogenesis of experimental diabetic retinopathy

Sirman, Ya. V.; Savytskyi, I. V. (2020)

The aim of the study was to analyze changes in erythrocyte diphosphoglycerate levels and Willebrand factor in the development of hypoxia and endothelial dysfunction in experimental diabetic retinopathy. The study was ...
Study of vasodilation processes

Sirman, Ya. V.; Savytskyi, I. V. (2019)

To date, the key role of endothelial dysfunction in the occurrence and progression of diabetes mellitus and diabetic retinopathy has been proven. The study was performed on white Wistar rats weighing 180-200 g. According ...
Analgesic and anti-inflammatory activity of vanillin derivatives

Бойко, Ю. А.; Нестеркина, М. В.; Шандра, А. А.; Кравченко, И. А.; Boiko, Y. A.; Nesterkina, M. V.; Shandra, A. A.; Kravchenko, I. A. (2019)

Анальгетическая активность производных 4-гидрокси-3-метоксибензальдегида (ванилина) с различными фармакоформными группами изучена in vivo на моделях химически-индуцированной боли, вызванной субплантарным введением агонистов ...
Peculiarities of the condition of vascular platelic hemostasis in diabetic retinopathy and diabetic nephropathy in rats

Hrytsan, I. I.; Savytskyi, I. V.; Preys, N. I.; Sarakhan, V. M.; Moiseieva, G.; Yermuraki, P. (2020)

The article presents experimental data on the study of changes in vascular platelet hemostasis in rats with experimental DR and DN on the background of type 2 diabetes. It is established that microcirculatory complications ...
Oxidative stress suppression contributes to antiseizure action of axitinib and rapamycin in pentylenetetrazol-induced kindling

Poshyvak, O. B.; Pinyazhko, O. R.; Godlevsky, L. S. (2021)

Rapamycin and axitinib block different kinases in signaling pathways such as PI3K-Akt-mTOR and BDNF-TrkB, respectively. Both have antiseizure and antioxidative actions, which justify studying the combined effects of these ...
Oxidative stress suppression contributes to antiseizure action of axitinib and rapamycin in pentylenetetrazol-induced kindling

Poshyvak, O. B.; Pinyazhko, O. R.; Godlevsky, L. S. (2021)

Rapamycin and axitinib block different kinases in signaling pathways such as PI3K-Akt-mTOR and BDNF-TrkB, respectively. Both have antiseizure and antioxidative actions, which justify studying the combined effects of these ...
Axitinib displays antiseizure activity on pentylenetetrazol – induced kindling mode

Poshyvak, O. B.; Pinyazhko, O. R.; Godlevsky, L. S. (2021)

This work aimed to investigate the effects of a specific inhibitor of vascular endothelial growth factor receptor generic axitinib upon pentylenetetrazol (PTZ) - induced kindled and acute convulsions and to compare ...
Influence of transcranial magnetic stimulation on spike-wave discharges in a genetic model of absence epilepsy

Godlevsky, L. S.; Kobolev, E. V.; van Luijtelaar, E. L. J. M.; Coenen, A. M. L.; Stepanenko, K. I.; Smirnov, I. V. (2006)

Transcranial magnetic stimulation (TMS) impulses, (0.5 Hz, 3 impulses) were presented at threshold intensity to male WAG/Rij rats. One group received stimuli, which involved motor responses of hindlimbs, rats of the second ...
Diazepam and electrical stimulation of paleocerebellar cortex inhibits seizures in pentylenetetrazol kindled rats

Godlevsky, L. S.; Shandra, O. O.; Pervak, M. O.; Shandra, A. A. (2020)

The cerebellum is a potent anti‑epileptic target for deep brain stimulation in patients with drug‑resistant epilepsy. The effects of such stimulation, however, may also favor seizure activity. Our goal was to investigate ...
Rat skin inflammation markers change in response to calcium hydroxyapatite and hyaluronic acid administration

Larkina, S. A.; Seletskaya, A. V.; Makarenko, O. A.; Vastyanov, R. S. (2021)

In the research, the level of some markers of skin inflammation in Wistar rats was examined after injection of calcium hydroxyapatite and hyaluronic acid drugs of various concentrations, where the nature, degree, extent ...
Грани дистанционного обучения в медицине

Котюжинская, С. Г.; Гончарова, Л. В.; Уманский, Д. А.; Kotiuzhynska, S.; Goncharova, L.; Umanskiy, D.; Котюжинська, С. Г.; Гончарова, Л. В.; Уманський, Д. А. (2021)

Вступление. Вопрос о применении дистанционной формы обучения в медицинских учебных заведениях остается дискуссионным. С одной стороны, преимуществами дистанционного образования является возможность обучения сразу большого ...
Исследование влияний на процессы памяти антагонистов серотониновых рецепторов

Онуфиенко, О. В.; Русакова, М. Ю.; Кащенко, О. А.; Шандра, О. А. (2021)

Ноотропные препараты представляют собой сравнительно новую и перспективную группу лекарственных средств, которые широко внедряются в медицинскую практику. В медицинской практике появляются новые ноотропные препараты разных ...

Now showing items 121-140 of 307

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Видання іноземною мовою. Кафедра фізіології, патологічної фізіології, медичної фізики та інформатики: Recent submissions

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