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Перегляд Кафедра фізіології та біофізики за назвою

Зараз показуються 1-20 з 318

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4f-Luminescence of lanthanide ions in regioisometric corrole complexes

Semenishyn, N.; Smola, S.S.; Rusakova, M. Yu.; Rusakova, N. V.; Семенішин, М. М.; Смола, С. С.; Русакова, М. Ю.; Русакова, Н. В. (2021)

Porphyrin compounds with Nd(III), Yb(III) and Cu(II), Zn(II), Pd(II) were obtained on the basis of ditopic porphyrins, the structure of which allowed obtaining various heterometallic complexes. Specified f-metals were chosen ...
6 Hz repeated transcorneal stimulations in rats failed to induce kindling seizures

Arabadzhy, D. R.; Ryabenka, O. D.; Shcheglov, I. A.; Prybolovets, K. O.; Kashchenko, O. A.; Bidnyuk, V. K. (2024)

Our work aimed to produce kindled seizures with transcorneal 6‐Hz electrical stimulation (ES) (32 mA 6 Hz for 3 seconds (GRASS stimulator, Astro.Med.Inc., USA) that was performed daily 5 times per week. Al‐ together 25 ...
Analgesic and anti-inflammatory activity of vanillin derivatives

Boiko, Yu. A.; Nesterkina, M. V.; Shandra, A. A.; Kravchenko, I. A. (2019)

The analgesic activity of 4-hydroxy-3-methoxybenzaldehyde (vanillin) derivatives with different pharmacophore groups were studied in vivo in models of chemically induced pain induced by subplantar administration of the TRP ...
Anti-Inflammatory Effect of Semisolid Dosage Forms Containing Capsaicin

Boiko, Yu. A.; Kravchenko, I. A.; Mohammad Ayat; Shandra, A. A. (2016)

Capsaicin is alkaloid found primarily in the fruit of the Capsicum genus. Capsaicin and its analogues have been used in topical creams and patches to treat chronic pain and inflammation. Objectives: The paper deals with ...
Anticonvulsant effect of resveratrol in the conditions of acute corasolinduced seizures

Boiko, Yu.; Shandra, A.; Boiko, O. (2017)

The incidence of seizure syndromes including those epilepsy associated actualizes the search of new anticonvulsants. The compounds of plant origin are of considerable interest in this respect. Such biologically active ...
Antiseizure effects of cerebellum is mediated via peroxisomal proliferator-activated γ-receptors (PPAR-γ)

Godlevsky, L. S.; Pervak, M. P.; Lyashenko, A. V.; Bidnyuk, K. A. (2021)

Earlier on the model of pentylenetetrazol (PTZ) – induced kindling it was shown that blockade of PPARγ with bisphenol A diglycidyl ether (2,2’-[(1-methylethylidene) bis(4,1- phenyleneoxymethylene)] bis-oxirane (BADGE) ...
Antiseizuree effectiveness of nicotinamid and diazepam increased after brain transcranial direct current stimulation (tDCS)

Prybolovets, K. O.; Pastuhov, O. O.; Budigay, N. S.; Kibysh, Ya. A.; Godlevsky, L. S. (2024)

tDCS of the cerebellum prevented PTZ‐kindled seizures, and such an effect was strengthened after diazepam administration. The work aimed to investigate the pronouncement of antiseizure effects of nicotinamide and diazepam ...
Anxiolytic and antidepressive effects of electric stimulation of the paleocerebellar cortex in pentylenetetrazol kindled rats

Godlevsky, L. S.; Muratova, T. N.; Kresyun, N. V.; Van Luijtelaar, G.; Coenen, A. M. (2014)

Anxiety and depression are component of interictal behavioral deteriorations that occur as a consequence of kindling, a procedure to induce chronic epilepsy. The aim of this study was to evaluate the possible effects of ...
Aplication of the continuous wavelet transformation (CWT) for the automatic detection of interital epileptic discharges

Prybalovets, T. V.; Kresyun, N. V.; Bidnyuk, K. A.; Nenova, O. M.; Muratova, T. M.; Chernetska, G. V.; Прибаловець, Т. В.; Кресюн, Н. В.; Біднюк, К. А.; Нєнова, О. М.; Муратова, Т. М.; Чернецька, Г. В. (Odessa National Medical University, 2016)

This article describes an example of using continuous wavelet-transforming for automatic detection of epileptic events on interictal EEG data. The principle of automatic calculation of wavelet-coefficients band and ...
Application of Mobile Photography with Smartphone Cameras for Monitoring of Early Caries Appearance in the Course of Orthodontic Correction with Dental Brackets

Godlevsky, L.; Bidnyuk, E.; Bayazitov, N.; Kresyun, N.; Kovalenko, A.; Lyashenko, A.; Balyko, V. (2013)

The objective of this research was observation of patients, who underwent orthodontic tooth alignment correction with dental brackets, for the detection of white spots, (early stage of caries) based on the digital photographs ...
Applying bioactive compounds of Pseudomonas SPP. For medicine substance development

Marchenko, M.; Rusakova, M. (2024)

Infectious diseases are still a worldwide important problem. This fact has led to the characterization of new biomarkers that would allow an early, fast and reliable diagnostic and targeted therapy. In this context, ...
Axitinib displays antiseizure activity on pentylenetetrazol – induced kindling mode

Poshyvak, O. B.; Pinyazhko, O. R.; Godlevsky, L. S. (2021)

This work aimed to investigate the effects of a specific inhibitor of vascular endothelial growth factor receptor generic axitinib upon pentylenetetrazol (PTZ) - induced kindled and acute convulsions and to compare ...
Blockade of Н3 histamine receptors facilitates antiseizure action of Pentoxyphilline

Prybolovets, K. O.; Poshyvak, O. B.; Pervak, M. P.; Yehorenko, O. S.; Godlevsky, L. S. (2022)

Considering the important role of inflammation in epilepsy development is reasonable to investigate the effects of combined usage of different modulators of neural inflammation. The work aimed to investigate the effects ...
Cardiotoxic effect of bleomycin with a single administration in the experiment

Bestanchuk, E.; Gozhenko, A.; Kashchenko, O.; Narbutova, T.; Berezovskyi, O.; Zаkharova, V. (2021)

The aim of the study was to evaluate the effect of a single injection of bleomycin on the heart Material and methods. The study was conducted in the Research Institute of Transport Medicine during 2016-2021. The experimental ...
Cerebellar contribution to absence epilepsy

Godlevsky, L. S.; Pinyazhko, O. R.; Poshyvak, O. B. (2020)

The new aggregate data analyses revealed the earlier missing role played by the cerebellum long-term electrical stimulation in the absence epilepsy. Neurophysiologic data gained by authors favor that cerebellar serial deep ...
Cerebellar transcranial direct current stimulation (tDCS) and pitolisant prevented behavioral and neuroinflammatory disturbances in pentylenetetrazol (PTZ) kidnling

Pervak, M. P.; Yehorenko, O. S.; Onuphrienko, O. V.; Varava, S. V.; Litvinenko, M. V.; Godlevsky, L. S. (2024)

The work aimed to investigate behavioral mani‑festations in PTZ‑kindled rats under combined treat‑ment with the histamine H3 receptor inverse agonist pitolisant and mTOR blocker rapamycin. Kindling was produced in Wistar ...
COVID-19-Related Age Profiles for SARS-CoV-2 Variants in England and Wales and States of the USA (2020 to 2022): Impact on All-Cause Mortality

Jones, Rodney P.; Ponomarenko, A. (2023)

Since 2020, COVID-19 has caused serious mortality around the world. Given the ambiguity in establishing COVID-19 as the direct cause of death, we first investigate the effects of age and sex on all-cause mortality during ...
Cumulative cardiotoxic effect of bleomycin in experiment

Gozhenko, A.; Bestanchuk, O.; Kaschenko, O.; Narbutova, T. (2021)

The aim of the study was to evaluate the cumulative toxic effect of bleomycin under experimental conditions Material and Methods. The study was conducted in the Research Institute of Transport Medicine during 2016-2021. ...
Cytokines and Absence Seizures in a Genetic Rat Model

Luijtelaar, G.; Lyashenko, S.; Vastyanov, R.; Verbeek, G.; Oleinik, A.; Rijn, C.; Volokhova, G.; Shandra, A.; Coenen, A.; Godlevsky, L. (2012)

We investigated the role of two cytokines, IL-1β and TNF-α, in the development of absence seizures using a genetic model of absence epilepsy in WAG/Rij rats. We administered these cytokines to animals systemically and ...
Daytime sleep-wakefulness cycle disturbances are effectively reversed with pitolisant in pentylenetetrazol-kindled rats

Yehorenko, O. S.; Pervak, M.; Latypov, K. A.; Prybolovets, K.; Shcheglov, I. A.; Godlevsky, L. S. (2023)

Chronic brain eptisation induces sleep-wakefulness (SW) disturbances. The work aimed to investigate SW cycle in pentylenetetrazole (PTZ)- kindled rats under combined treatment with the histamine H₃ inverse agonist ...

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