Informativeness of phenotypic features of connective tissue dysplasia in children with peritoneal adhesions

Abstract

Connective tissue dysplasia can be realized with a large number of clinical variants, and accordingly, excessive postoperative adhesion formation can be considered as a manifestation of dysplastic-dependent processes. In the predominant number of surveyed children (93.8%) CTD has developed on the background of existing connective tissue dysplasia syndrome, i.e. the presence of external signs of this condition may serve as a predictor of postoperative complications of adhesions in children. Direct correlation between the number of CTD phenotypic characters and the prevalence of intra-abdominal adhesions was determined. In our view, it allows to detect children at risk of peritoneal adhesions on the basis of external features that can be identified during general examination and do not require additional time or equipment. Accordingly, the surgical treatment of children with signs of CTD syndrome requires an integrated approach and the application of measures to prevent excessive adhesion formation, including intraoperative use of anti-adhesive gels.