Abstract:
Aminomethanesulfonic acid (I) and its N-methyl- (II), N-(2-hydroxy)ethyl- (III), N-(tert-butyl)- (IV), N-benzyl- (V), and 4-(N-phenylaminomethyl)phenyl- (VI) derivatives (V and VI not previously reported) were synthesized and characterized by elemental analysis and IR and mass spectroscopy. The in vitro antioxidant activities of aminomethanesulfonic acids I-VI were found to be comparatively weak. Compounds IV and V suppressed statistically significantly reproduction of influenza virus strains A/Hong Kong/1/68 (H3N2) and A/PR/8/34 (H1N1) in chorioallantoic membrane tissue culture.
