Differences in the effects of milk thistle fruits on the activity of transport of glucose and glycine in the small intestine of two generations of posterity of irradiated rats

Abstract

As a means of protecting the body from radiation, herbal preparations have low toxicity, a mild prolonged effect and a wide spectrum of action. Among them, the milk thistle fruits Silybum marianum (L.) Gaertner, which are the basis for many hepatoprotectors due to the presence of the silymarin flavonoid and a complex of biologically active substances with membranotropic properties, attract attention. The small intestine, in which the final processes of absorption of nutrients occur, is one of the most radiosensitive organs. We hypothesized that the biologically active substances of milk thistle fruits can have a membranotropic effect also on enterocytes. Thus, the aim of the study was to research the effect of milled milk thistle fruits on the absorption of glucose and glycine in the small intestine of 2 generations from irradiated male rats.