Abstract:
It is known that malignant diseases are one of the most important medico-biological
and socio-economic problems in the world and, especially, in Ukraine. Cancer is a worldwide
problem; about 2.9 million new cases of the disease are registered annually in the developed
countries of the world and more than 3 million in developing countries. The causes of the face
skin cancer like all other malignant neoplasms are not fully established. The pesticides are
known to provide a wide range of effects on the human body and, in particular, a complex of
various types of biological activity - cytogenetic, carcinogenic, teratogenic, embryotoxic, etc.
The main purpose of this work is to determine the consequences of agrochemicals use in 1970-
1990th on the human skin malignant neoplasms incidence increase after 1990 based on the
statistical indicators evaluation in the department of dermatology and in the Zonal
agrochemical laboratory. The characteristics of main factors of the anthropogenic impact on
the environment, abundance and residual quantity of pesticides in the geological habitat of the
Odessa region were examined. According to the method of correlation analysis the relation
between application of pesticides and sickness rate of the cancer of the skin of face and body. Authors conclude that Odesa region geological environment contamination with
polyagrochemicals (soil cover, bottom sediments of reservoirs and watercourses, as well as
groundwater) leads to toxic pollution of the biosphere and has a carcinogenic effect on the
body, which ultimately leads to an increase in episodes of malignant neoplasms of the skin of
the body in the Odesa region. The comparative analysis showed that the sickness rate of the
cancer of skin of body in the village and urban sector is approximately equal. The uncontrolled
use of pesticides from 1960 to 1990 had a negative impact on the formation of malignant
neoplasms indexes in the Odesa Region, which increased significantly, especially over the last
two decades.
