Abstract:
The article presents the results of studies of the effect of radon and sulfide mineral waters (MW) on Wistar rats with experimental arthrosis. materials and methods. Rats
were randomized into 4 groups. Group 1 consisted of intact rats (control group). In the
remaining three groups, a model of knee arthrosis was reproduced using dexamethasone
injections. Group 2 consisted of rats with untreated pathology. Group 3 consisted of rats
using radon MW procedures, and group 4 consisted of rats using sulfide MW. Results.
Morphological studies have determined that using radon and sulfide MW has a curative
effect on the structural and functional organization of the joint and cartilage - the manifestations of inflammation in the knee joints are significantly reduced, dystrophic manifestations disappear, and reparative processes in cartilage improve. There are signs of an
improvement in the state of metabolic processes in the body of rats: the balance in the
lipid peroxidation and antioxidant systems is restored, and the indicators of the processes
of energy supply of transmembrane transport (according to the activity of magnesiumdependent Na+/K+-ATP-ase and Ca2+-ATP-ase) and protein exchange.Conclusion. Based
on the data obtained, it was concluded that both applied MWs have a unidirectional, but
somewhat different in strength, curative effect on the course of experimental arthrosis,
which is due to different mechanisms of the biological action of radon and hydrogen sulfide.
