Короткий опис (реферат):
More than 20 % of people over the age of 50 suffer from osteoporosis. Lipids play an
important role in the pathogenesis of osteoporosis.
Background. To investigate the effect of ordinary (high-linoleic) sunflower oil (OSO)
on the state of periodontal bone tissue.
Methods. In 5 series of experiments, determine the mineralization activity of the
alveolar appendix of the mandible rats that were obtained with feed 5 or 15 percent of OSO
for from 22 to 75 days. Mineralizing activity was determined by the ratio of activity of
alkaline and acid phosphatase. In liver lipids (fractions of phospholipids and free fatty acids)
were determined by the content of long-chain polyunsaturated fatty acids (LCPUFA) by the
gas chromatographic method.
Results. A decrease in mineralizing activity in OSO consumption, especially when
using a feed with 15 % of OSO against a dysbiosis or metabolic syndrome. A significant (almost 10 times) is shown to reduce the content of ω-3 PUFA in fraction of phospholipids of
the liver of rats receiving a diet with a content of OSO.
Conclusion. Sunflower oil reduces the mineralizing activity of periodontal bone tissue
by reducing the endogenous biosynthesis of ω-3 PUFA.
