Possibility of early diagnosis of complications of optic nerve neuritis in patients with anterior uveitis according to coherent tomography of the eye orbit

Abstract

The aim of the study was to determine the possibility of early diagnosis of optic neuritis in patients with anterior uveitis by determining the diameter of the optic nerve using computed tomography of the orbit. The examination and treatment included 114 patients with anterior uveitis and 36 patients with anterior uveitis complicated by optic neuritis. A standard ophthalmological examination was performed and also ocular electrical impedance studies (relative ocular pulse blood filling and ocular blood flow velocity, determination of the diameter of the optic nerve by coherence tomography were performed An increase in the diameter of the optic nerve in eyes with anterior uveitis complicated by neuritis by 7.2, 11.5 and 18.3% was shown relative to paired eyes when measured retrobulbar, in the middle section and in the orbital region. An increase in volumetric pulse blood filling was found in anterior uveitis in the diseased eye relative to the paired eye, especially pronounced in the presence of neuritis (65.4%). The obtained data indicate the possibility of predicting the development of neuritis against the background of anterior uveitis with an increase in the diameter of the optic nerve (according to computed tomography) and the presence of a vascular reaction in the focus of inflammation (according to the results of ocular electrical impedance studies).