The mechanism of realization of antiseizure effects of cerebellar electrical stimulation

Bidnyuk, V. K.; Pervak, M. P.; Poshyvak, O. B.; Yehorenko, O. S.; Varava, S. V.; Godlevsky, L. S.; Haustov, O. O.

dc.contributor.author	Bidnyuk, V. K.	en
dc.contributor.author	Pervak, M. P.	en
dc.contributor.author	Poshyvak, O. B.	en
dc.contributor.author	Yehorenko, O. S.	en
dc.contributor.author	Varava, S. V.	en
dc.contributor.author	Godlevsky, L. S.	en
dc.contributor.author	Haustov, O. O.	en
dc.date.accessioned	2022-12-09T09:32:13Z
dc.date.available	2022-12-09T09:32:13Z
dc.date.issued	2022
dc.identifier.citation	The mechanism of realization of antiseizure effects of cerebellar electrical stimulation / V. K. Bidnyuk, M. P. Pervak, O. B. Poshyvak et al // Acta neurobiologia experimentalis: II 12th Neuronus 2022 Neuroscience Forum, 15–17 october 2022, Krakov, Poland. Vol. 82. P. 51–52.	en
dc.identifier.uri	https://repo.odmu.edu.ua:443/xmlui/handle/123456789/11717
dc.description.abstract	We have reported that electrical stimulations of cerebellar structures resulted in the heightened antiseizure effectiveness of diazepam against pentylenetetrazol (PTZ)-kindled seizures. Such effects might be explained by the increased antioxidant mechanisms in the brain tissue, which counterparts oxidative stress, as a fundamental pathogenetic mechanism of chronic epileptic activity. The work aimed to investigate the state of antioxidant defense in the cerebral cortex of PTZ-kindled rats under electrical stimulations (100 Hz, 0,25 ms, 50-100 mcA, 2,5 s) of the paleocerebellar cortex (V-VII lobules).	en
dc.language.iso	en	en
dc.subject	antiseizure effects	en
dc.subject	cerebellar electrical stimulation	en
dc.subject	diazepam	en
dc.subject	pentylenetetrazol	en
dc.title	The mechanism of realization of antiseizure effects of cerebellar electrical stimulation	en
dc.type	Article	en