Короткий опис (реферат):
COVID-19 pandemic is recognized as a present day major public health burden. Risk
factors for developing a more severe course of COVID-19 include increased levels of Creactive protein and D-dimer. Pulmonary embolism (PE) is challenging in patients with
COVID-19. The purpose: to analyze clinical and paraclinical manifestations of PE in patients
with COVID-19 in order to develop a system for its early diagnosis, prediction of
complications, prevention and treatment. 52 patients aged 28 - 81 y.o. with a diagnosis "Acute
respiratory disease COVID-19" have been examined during 2020-2021. (98.08±1.9)% of PE
patients had a history of one or more comorbidities, including obesity (80.77%), coronary
heart disease (96.15%), hypertension (98.08%), peripheral arteries (92.3%), type 2 diabetes
mellitus (48.08%). Evaluation of laboratory parameters revealed increasing lymphocytopenia,
leukocytosis, neutrophilia, thrombocytopenia (p<0.05). Biochemical parameters showed high
CRP, increase in creatinine, decrease in glomerular filtration rate (p<0.05). A direct
relationship was found between overweight and an increase in the content of C-RP in
COVID-19 and PE patients. Conclusions: age over 65, hypertension and obesity are risk
factors for severe course of COVID-19 and PE.