Abstract:
The article presents experimental data on the study of changes in vascular platelet
hemostasis in rats with experimental DR and DN on the background of type 2 diabetes. It is
established that microcirculatory complications of type 2 diabetes are characterized by a
decrease in platelet count, increased aggregation capacity. In the study of induced platelet
aggregation, the polarity of the results of the study was proved, which indicates the
dependence of complications on the functional state of vascular platelet hemostasis, primarily
due to stimulated, depleted platelets and the corresponding number of intact platelets. More
pronounced changes in vascular-platelet hemostasis on the background of type 2 diabetes in
rats with DN compared with the group of animals that reproduced DR.
