dc.contributor.author |
Godlevsky, L. S. |
|
dc.contributor.author |
Kobolev, E. V. |
|
dc.contributor.author |
van Luijtelaar, E. L. J. M. |
|
dc.contributor.author |
Coenen, A. M. L. |
|
dc.contributor.author |
Stepanenko, K. I. |
|
dc.contributor.author |
Smirnov, I. V. |
|
dc.date.accessioned |
2021-12-08T11:18:58Z |
|
dc.date.available |
2021-12-08T11:18:58Z |
|
dc.date.issued |
2006 |
|
dc.identifier.citation |
Influence of transcranial magnetic stimulation on spike-wave discharges in a genetic model of absence epilepsy / L. S. Godlevskya, E. V. Koboleva, E. L. J. M. van Luijtelaarb, A. M. L. Coenenb, K. I. Stepanenkoa, I. V. Smirnov // Indian Journal of Experimental Biology. 2006. Vol. 44. P. 949–954. |
uk_UA |
dc.identifier.uri |
https://repo.odmu.edu.ua:443/xmlui/handle/123456789/10511 |
|
dc.description.abstract |
Transcranial magnetic stimulation (TMS) impulses, (0.5 Hz, 3 impulses) were presented at threshold intensity to male
WAG/Rij rats. One group received stimuli, which involved motor responses of hindlimbs, rats of the second group received
sham stimulation. Electrocorticograms (ECoG) were recorded before and up to 2 hr from the moment of transcranial
magnetic stimulation. It was established that such stimulation engendered a reduction of spike-wave discharge (SWD) bursts
duration. This effect was most pronounced in 30 min from the moment of cessation of stimulation, when a decrease of
31.4% was noted in comparison with sham-stimulated control group. The number of bursts of spike-wave discharges was
reduced, but did not reach significant difference when compared both with pre-stimulative base-line level and with shamstimulated control rats. Bursts of spike-wave discharges restored up to pre-stimulative level in 90-150 minutes from the
moment of cessation of transcranial stimulation. It can be concluded that transcranical magnetic stimulation possessed an
ability to engender short-time suppression of bursts of spike-wave discharges in WAG/Rij rats. |
uk_UA |
dc.language.iso |
en |
uk_UA |
dc.subject |
Absence epilepsy |
uk_UA |
dc.subject |
Spike-wave discharges |
uk_UA |
dc.subject |
Transcranial magnetic stimulation |
uk_UA |
dc.title |
Influence of transcranial magnetic stimulation on spike-wave discharges in a genetic model of absence epilepsy |
uk_UA |
dc.type |
Article |
uk_UA |