• Changes of protein expression of platinum resistance indicators under the influence of hyperthermia during the HIPEC procedure in recurrent ovarian cancer 

  Rozhkovska, N. M.; Chetverikov, S. H.; Chetverikov, M. S.; Chetverikova-Ovchynnyk, V. V.; Рожковська, Н. М.; Четверіков, С. Г.; Четверіков, М. С.; Четверікова-Овчинник, В. В. (2025)

  Ovarian cancer relapse and death are usually caused by acquired drug resistance. The mechanisms of platinum resistance are multifactorial. Excision repair cross-complementation group 1 (ERCC1) is a protein critical in ...
• Advances in surgical techniques for the treatment of giant hiatal hernia 

  Grubnik, V. V.; Korchevyi, D. V.; Grubnik, V. V.; Parfentiev, R. S.; Bugrydze, Z. D.; Грубник, В. В.; Корчевий, Д. В.; Грубник, В. В.; Парфентьєв, Р. С.; Бугридзе, З. Д. (ONMedU, 2025)

  Laparoscopic surgery for large and giant hiatal hernias is associated with significant technical difficulties. This study compared outcomes of two surgical approaches: the use of mesh implants and relaxing incisions of the ...
• Impact of state health prevention financing programs on the activities of health protection environments in Ukraine 

  Nikitenko, R.; Panchenko, H.; Dulina, O.; Latysheva, V.; Liubinska, O.; Нікітенко, Р.; Панченко, Г.; Дуліна, О.; Латишева, В.; Любінська, О. (2025)

  The article examines the features of the application of correlation-regression analysis to identify the impact of state health prevention financing programs on the activities of health protection entities in Ukraine. The ...
• Experience in performing laparoscopic robot-assisted prostatectomy in the surgical treatment of benign prostatic hyperplasia 

  Tserkovniuk, R. H.; Gorovyi, V. I.; Sosnin, M. D.; Moraru–Burlesku, R. P.; Chaika, O. M.; Kapshuk, V. M.; Taheiev, V. R.; Церковнюк, Р. Г.; Горовий, В. І.; Соснін, М. Д.; Морару–Бурлеску, Р. П.; Чайка, О. М.; Капшук, В. М.; Тагеєв, В. Р. (2025)

  Aim. To evaluate the immediate (in-hospital) outcomes of laparoscopic robot-assisted prostatectomy in the surgical treatment of large benign prostatic hyperplasia (greater than 80 cm3 ). Materials and methods. The study ...
• Transanal endoscopic microsurgery with the fluorescence lymphangiography: program 

  Vorotyntseva, K.; Grubnyk, V. (2025)

  In the program 33rd international congress of the European Association for Endoscopic Surgery and other interventional techniques presents the topic transanal endoscopic microsurgery with the fluorescence lymphangiography.
• Effectiveness of relaxing excision of diaphragm in patients with large and giant hiatal hernias 

  Grubnyk, V.; Ilyashenko, V.; Korchovyi, D. (2025)

  Background: Laparoscopic repair of giant hiatal hernias (HH) presents significant challenges, with traditional techniques often associated with high recurrence rates (30-50%) and complications. Objective: To evaluate the ...
• The use of cervical mediastinoscopy in retrosternal goiter surgery 

  Parfentiev, R.; Grubnyk, V.; Grubnik, V. (2025)

  Background. Retrosternal goiter presents a complex surgical challenge due to its anatomical location and potential for significant complications. Modern surgical techniques, including cervical mediastinoscopy, aim to ...
• Transanal endoscopic microsurgery with the fluorescence lymphangiography 

  Vorotyntseva, K.; Grubnik, V.; Grubnyk, V. (Surgical Endoscopy, 2025)

  Background Early-stage rectal cancer can be managed with transanal endoscopic microsurgery (TEM) as a minimally invasive alternative to radical surgery. However, a major limitation of TEM is the potential for occult ...
• Quintip Recordati initial data concerning the peculiarities of human papillomavirus infection epidemiology in Ukraine and the prospects for its prevention 

  Rybin, A. I.; Osyk, V. V.; Vastyanov, R. S.; Liskovsky, S. V.; Artyomenko, V. V.; Рибін, А. І.; Осик, В. В.; Вастьянов, Р. С.; Лісковський, С. В.; Артьоменко, В. В. (Полтавський державний медичний університет та Всеукраїнська громадська організаця "Наукове товариство анатомів, гістологів, ембріологів і топографанатомів України", 2025)

  The purpose of the study was to evaluate the human papillomavirus infection prevalence among women in different regions of Ukraine using the Quintip Recordati database. The Quintip Recordati database data, containing 195 ...
• Interviews with Outstanding Authors 

  Chaika, O.; Zhu, S.; Li, B. (2025)

  Oleksander Chaika, MD, PhD, is an Associate Professor of Surgery at Odesa National Medical University in Ukraine. He graduated from the same university in 2007 and completed clinical training in urology, endoscopy, oncology, ...
• The effectiveness of laparoscopic choledochoduodenostomy for management of persistent common bile duct stones and advanced malignant obstructive jaundice 

  Grubnik, V. V.; Grubnik, Y. V.; Ilyashenko, V. V.; Grubnik, M. Y.; Grubnyk, V. V.; Грубнік, В. В.; Грубнік, Ю. В.; Ільяшенко, В. В.; Грубнік, М. Ю.; Грубник, В. В. (2025)

  Endoscopic clearance of common bile duct (CBD) stones and stenting for distal biliary obstruction are standard treatments, but can fail in cases of large calculi or advanced malignancy. Laparoscopic choledochoduodenostomy ...
• A case report of cytoreductive surgery of metastatic adrenal cancer in a patient with tumor progression 

  Chaika, O.; Maksimovskyi, V.; Smolyk, D.; Ochigava, D. (2025)

  Background: Adrenocortical cancer is a rare malignancy with high risk of relapse and disease progression. The approaches to the treatment of relapse cases are not sufficiently clearly defined by current clinical guidelines. Case ...
• Peculiarities of metabolic and autonomicendocrine accompaniments of urate-losing/retaining kidneys 

  Ishchenko, V. S.; Anchev, A. S.; Ivanov, D. D.; Zukow, W. (2024)

  This publication initiates the project "Neuro-endocrine regulation of the clearance of nitrogenous metabolites". The first stage of project implementation is the clarification of peculiarities of metabolic and neuro-endocrine ...
• Repeated operations for severe refl ux esophagitis after gastric tube resection 

  Grubnik, V. V.; Medvedev, O. V.; Ishchenko, V. S. (2025)

  Objective. To evaluate the effectiveness of repeated surgical interventions in the treatment of gastroesophageal reflux disease after gastric tube resection in patients with morbid obesity. Materials and methods. The ...
• Neuro-endocrine regulation of the clearance of uric acid 

  Ishchenko, V. S.; Gozhenko, A. I.; Іщенко, В. С.; Гоженко, А. И. (2025)

  On the first stage of project "Neuro-endocrine regulation of the clearance of nitrogenous metabolites" implementation, we found out of peculiarities of metabolic and neuro-endocrine accompaniments of urate-losing and ...
• Peculiarities of neuro-endocrine-immune accompaniments of urate-losing/retaining kidneys 

  Ishchenko, V. S.; Anchev, A. S.; Іщенко, В. С.; Анчев, А. С. (2024)

  On the first stage of project “Neuro-endocrine regulation of the clearance of nitrogenous metabolites” implementation, we found out of peculiarities of metabolic and neuro-endocrine accompaniments of urate-losing and ...
• Potential of transanal endoscopic surgery in the management of early rectal cancer 

  Vorotyntseva, K. O.; Grubnik, V. V.; Воротинцева, К. О.; Грубнік, В. В. (2025)

  Relevance. Transanal surgery for rectal pathology remains relatively rare. Transanal endoscopic surgery (TES) is performed at the early stages of rectal cancer. However, the issue of lymphogenic metastasis is still ...
• Skin injury surface cytology dynamics changes in experimental wound process 

  Muraviov, P. Т.; Bespalko, М. H.; Zaporozhchenko, B. S.; Муравйов, П. Т.; Беспалько, М. Г.; Запорожченко, Б. С. (2025)

  Long-persisting chronic wounds represent a significant challenge for general surgery specialists. The purpose of the study was to determine the characteristics of cellular composition changes along the wound surface during ...
• Diagnostic and treatment approaches of acute adhesion intestinal obstruction in pregnant women and women in labor in the conditions of full-scale war in Ukraine 

  Mishchenko, V. V.; Mishchenko, V. P.; Rudenko, I. V.; Goriachiy, V. V.; Міщенко, В. В.; Міщенко, В. П.; Руденко, І. В.; Горячий, В. В. (2025)

  Diagnostic and treatment approaches of acute adhesion intestinal obstruction in pregnant women and women in labor in the conditions of full-scale war in Ukraine. There are changes in the etiopathogenetic mechanisms and ...
• The effect of collagen hydrolyzate on wound healing in the conditions of experimental modeling of the course of the wound process in rats 

  Muraviov, P. T.; Bezpalko, M. H.; Davydov, D. M.; Муравйов, П. Т.; Беспалько, М. Г.; Давидов, Д. М. (2025)

  Despite the existence of multiple trends toward chronic wounds treatment, certain misunderstandings regarding the regeneration of connective tissue determine the need to address this problem. The aim of the study was to ...

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