Видання англійською мовою. Кафедра загальної і клінічної фармакології та фармакогнозії: Recent submissions

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The effect of a new combined feed on some physiological parameters of laboratory rats

Boiko, Yu.; Boiko, I. (2024)

For normal growth, development and vital activity, laboratory animals must receive a complete feed ration. A new feeding ration for rats was proposed, which is based on the use of combined feed PC 120-1. A comparison was ...
Peculiarities of the organs of the reproductive system of women of reproductive age with liver dysfunction under the influence of exogenous pollutants

Lobashova, O. I.; Nasibullin, B. A.; Baiazitov, D. M.; Kashchenko, O. A.; Koshelnyk, O. L.; Tregub, T. V.; Kovalchuk, L. Y.; Chekhovska, G. S.; Kachailo, I. A.; Gargin, V. V. (2023)

The widespread use of chemicals by modern society and the prevalence of harmful habits (alcoholism, tobacco smoking, drug addiction) leads to an unnaturally high intake of exogenous pollutants in the human body, which can ...
Pharmacology of post-traumatic stress disorder

Tregub, T.; Lytvynenko, M.; Kukushkin, V.; Chebotarova, S.; Oliynyk, N.; Gulbs, O.; Nazaryan, R. (2023)

The aim of this study was to evaluate current approaches to the pharmacotherapy of posttraumatic stress disorder. An information search was carried out in the databases PubMed, Ovid, EMBASE by keywords: “posttraumatic ...
Manifestations and treatment of atopic dermatitis in children

Kovpak, A.; Tsisak, A.; Eberle, L.; Zamkovaya, A.V.; Dabagh, N. (2024)

Atopic dermatitis is one of the most common allergic diseases that manifests itself in a severe form, affecting the skin. The disease is genetically determined and, unfortunately, is chronic. The manifestations of atopic ...
Phytochemistry analysis and medicinal use of plants of the genus Tagetes

Bohatu, S. I.; Prystupa, B. V.; Rozhkovskyi, Ya. V.; Богату, С. І.; Приступа, Б. В.; Рожковський, Я. В. (2024)

Given the significant interest in medicinal plants and their use in medicine, the question of finding new promising plants or using long-known plants in a new way is relevant. The growing demand for phytomedicines and ...
Features of protein metabolism during inflammation under terms of transdermal injection of ginger extract

Eberle, L. V.; Kobernik, O. O.; Kravchenko, I. A. (2018)

In recent years, interest in plant medicines, which have a mild physiological effect, minimal toxicity, non-addictive, absence of immunosuppression, the possibility of prolonged use, has increased. One of the medicinal ...
An impact of CYP3A4 *1B polymorphism on rifampicin metabolism

Poludenko, H. О.; Antonenko, P. B.; Полуденко, Г. О.; Антоненко, П. Б. (2017)

Until now, the enzyme systems responsible for biotransformation of the antituberculous drug rifampicin remain unknown. The aim of research was an investigation of the candidate enzymes involved in the biotransformation of ...
Прогностичне значення поліморфізму CYP3A4*1B у хворих на туберкульоз легень

Полуденко, Г. О.; Антоненко, П. Б.; Антоненко, К. О. (2024)

Метою дослідження стало вивчення комплексного впливу поліморфізму локусу CYP3A4*1В на вміст найбільш ефективних протитуберкульозних препаратів, ефективність та токсичність протитуберкульозної терапії. Матеріали і методи. ...
Pharmaceutical analysis and clinical application of combined medications for arterial hypertension

Strechen, S. B.; HirajiRime; Alaoui Chrifi Mohammed (2024)

Primary and secondary arterial hypertension is one of the most widespread pathologies of the cardiovascular system with a predominant lesion of vessels of the elastic smooth muscle type, which is accompanied by thickening ...
Dose-dependent effect of hexadecyl ester of ibuprofen on the model of formalin-induced inflammation

Prystupa, B. V.; Bogatu, S. I.; Kresyun, V. Y.; Boiko, I. A.; Unhurian, L. M.; Приступа, Б. В.; Богату, С. І.; Кресюн, В. Й.; Бойко, І. А.; Унгурян, Л. М. (2024)

Inflammation is a protective reaction of the organism to the damaging agent. Ibuprofen has anti-inflammatory, antipyretic, and anti-edema effect. But ibuprofen has also side effects. The main goal was to estimate the ...
Prognostic value of CYP3A4*1B polymorphism in patients with pulmonary tuberculosis

Poludenko, H. О.; Antonenko, P. B.; Antonenko, K. O.; Rozhkovskyi, Ya. V.; Shemonayeva, K. F.; Komlevoi, O. M.; Полуденко, Г. О.; Антоненко, П. Б.; Антоненко, К. О.; Рожковський, Я. В.; Шемонаєва, К. Ф.; Комлевой, О. М. (2024)

Previously it was found that in slow metabolizers according to CYP3A4*1G genotype after completion of in-patient stage of anti-tuberculosis treatment, the level of cytolysis and toxicity indexes was much higher than in ...
Study of propolis and wax moth extract as a preventive and therapeutic means for some diseases

Lakhmanyuk, Y. R.; Bodnarіuk, N. V.; Ustianska, O. V.; Eberle, L. V.; Tsisak, A. O.; Gritsuk, O. I.; Ulizko, I. V.; Лахманюк, Ю. Р.; Боднарюк, Н. В.; Устянська, О. В.; Еберле, Л. В.; Цісак, А. О.; Грицук, О. І.; Улізко, І. В.; Лахманюк, Ю. Р.; Боднарюк, Н. В.; Устянская, О. В.; Эберле, Л. В.; Цисак, А. А.; Грицук, А. И.; Улизко, И. В. (2024)

The paper presents an analysis of the literature data of the last decade on the clinical use of such apiproducts as propolis and wax moth extract as therapeutic and prophylactic agents. Interest in apitherapy and its ...
Features of lipid metabolism in membranes of rat cells at experimental traumatic brain injury on the background of chronic alcohol intoxication

Kresyun, V.; Godovan, V.; Sokolik, E.; Kresyun, N. (2022)

Alcohol intoxication is often the cause of traumatic brain injury. The purpose of the work was to study the features of lipid metabolism in erythrocytes and mitochondria of the cerebral cortex cell membranes of rats in ...
Training manual for self-training students 3 course of pharmaceutical faculty to a licensed test exam "Step - 1. Pharmacology" 2007–2023

Rozkovskiy, Y. V.; Shemonaeva, K.; Kresyun, V.; Antonenko, P.; Lobashova, K.; Ostapchuk, K.; Antonenko, K.; Al-Nadavi, N. (2023)

The study guide is intended for preparing students of the 3rd year of the Faculty of Pharmacy for the Step-1 licensing exam. The guide contains a database of test tasks from brochures of 2007-2023. The study guide consists ...
Methodical instructions for the practical classes in pharmacology for the third year students of medical faculty

Rozhkovsky, Ya. V.; Kresyun, V.; Antonenko, P.; Shemonaeva, K.; Ostapchuk, K.; Lobashova, K.; Antonenko, K.; Al-Nadawi, N. (2023)

Methodical instructions for the students of Medical faculty, who are learning pharmacology, contain the list of basic topics, questions and preparations, provided by the academic plan and program of Ministry of Health ...
Study of the anti-inflammatory properties of a thick extract of Tribulus terrestris L.

Yunusova, S.; Rozhkovskyi, Ya.; Prystupa, B.; Bohatu, S. (2023)

The most promising direction in the treatment of chronic prostatitis is the use of medicinal plants and preparations based on them, which contain natural compounds with a broad spectrum of pharmacological activity: ...
Prostate protective effect of thick extract of tribulus terrestris on the model of cryotrauma of the prostate gland in rats

Yunusova, S. I.; Bohatu, S. I.; Prysrupa, B. V.; Rozhkovskyi, Ya. V. (2023)

The search for modern prostate protectors based on native medicinal plant raw materials remains an urgent task of modern pharmacognosy and pharmacology. At the Department of Chemistry of Natural Compounds of the National ...
The study of carboxylic acids in flowers and leaves of Veronica chamaedrys L. and Veronica teucrium L.

Kovaleva, А.; Ilina, Т.; Raal, A.; Osmachko, A.; Goryacha, O.; Rozhkovskyi, Ya. (2020)

The genus Veronica (Veronica L.), family Plantaginaceae Juss. in the flora of Ukraine is represented by 64 species; Veronica chamaedrys L. and Veronica teucrium L. are widespread in the Kharkiv region. Plants are used in ...
Content of biologically active compounds in fruits of capsicum annuum L

Boyko, Yu.; Boyko, I. (2023)

The study of the chemical composition of natural raw materials allows not only to obtain data on the peculiarities of its structure and organization, but also to find new chemical compounds with useful qualities. The search ...
Hepatitis C Virus in people with experience of injection drug use following their displacement to Southern Ukraine before 2020

Yakovleva, A.; Kovalenko, G.; Redlinger, M.; Smyrnov, P.; Tymets, O.; Korobchuk, A.; Kotlyk, L.; Kolodiazieva, A.; Podolina, A.; Cherniavska, S.; Antonenko, P.; Strathdee, S. A.; Friedman, S. R.; Goodfellow, Ia; Wertheim, J. O.; Bortz, E.; Meredith, L.; Vasylyeva, T. I. (2023)

Due to practical challenges associated with genetic sequencing in low-resource environments, the burden of hepatitis C virus (HCV) in forcibly displaced people is understudied. We examined the use of field applicable HCV ...

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