Effects of cerebellar transcranial direct current stimulation upon kindled seizures depends upon PPARγ modulation

Pervak, M.; Godlevsky, L.

dc.contributor.author	Pervak, M.	en
dc.contributor.author	Godlevsky, L.	en
dc.date.accessioned	2021-02-08T05:50:05Z
dc.date.available	2021-02-08T05:50:05Z
dc.date.issued	2019
dc.identifier.citation	Pervak M., Godlevsky L. Effects of cerebellar transcranial direct current stimulation upon kindled seizures depends upon PPARγ modulation // Jornal of the neurological sciences. 2019. Vol. 405. P. 81.	en
dc.identifier.uri	https://repo.odmu.edu.ua:443/xmlui/handle/123456789/8751
dc.description.abstract	The purpose of the investigation was to estimate the effectiveness of peroxisomal proliferator-activated γ-receptors (PPARγ) modulation upon the antiseizure effects of transcranial direct current stimulation (tDCS). In rats with the kindling syndrome was induced by i.p. injections of pentylenetetrazol (PTZ; 30.0 mg/kg daily, for three weeks). For tDCS active electrode was located over cerebellar zone of cranium (10 mm2). The latent period of seizures induced by a test injection of PTZ (30 mg/kg) increased significantly (by 22.5% on average P b .05 vs. control) after tDCS (600 μA, 10.0 min, cathode on the skull surface).	en
dc.language.iso	en	en
dc.subject	PPARγ modulation	en
dc.subject	kindled seizures	en
dc.subject	transcranial direct current stimulation	en
dc.subject	kindling syndrome	en
dc.title	Effects of cerebellar transcranial direct current stimulation upon kindled seizures depends upon PPARγ modulation	en
dc.type	Article	en