Видання іноземною мовою. Кафедра загальної та клінічної патологічної фізіології: Recent submissions

Зараз показуються 61-80 з 94

Dynamics of biochemical markers in the pathogenesis of experimental bile pertonitis

Znamerovsky, S. G.; Savytskyi, I. V.; Dzygal, O. F.; Знамеровский, С. Г.; Савицкий, И. В.; Дзигал, А. Ф. (2020)

Biliary peritonitis (BP), which is a severe disease of the abdominal cavity in severity, prognosis and mortality rate depends on endogenous intoxication Systemic Inflammatory Reaction Syndrome (SIRS) is considered in ...
Interdependence investigation of dynamic between the von Willebrand factor and erythrocyte and leukocyte intoxication indices in experimental peritonitis

Savytskyi, I. V.; Tsypoviaz, S. V.; Lenik, R. G.; Bilash, O. V.; Zashchuk, R. H.; Miastkivska, I. V.; Zaiats, L. M. (2019)

The research was conducted on 175 white rats of reproductive age (3 months), weight of animals - 180-220 g. Animals were divided into 4 groups: Group 1 - 20 intact animals. Group 2 - 50 rats with simulated fecal ...
Comparative characteristics of inducible NO synthase inhibitor and nitric oxide donor in endothelial dysfunction correction caused by osteoarthrosis under experimental conditions

Orel, K. S.; Savitsky, I. V.; Miastkivska, I. V.; Zaiats, L. M. (2019)

Study have been carried out on white Wistar line rats (age – 3 months, weight – 180-220 g). According to the tasks the animals were divided into 7 groups. 1st group is intact (n = 20). 2nd group is rats, which were modeled ...
Interleukin-1 receptors antagonist intracerebral administrations anticonvulsive efficacy in conditions of kindling model of epileptogenesis

Vastyanov, R. S.; Stoyanov, A. N.; Krepec, Yu. S.; Dzygal, A. F.; Beseda, Ya. V.; Puchkova, A. V.; Вастьянов, Р. С.; Стоянов, О. М.; Крепец, Ю. С.; Дзигал, О. Ф.; Бєсєда, Я. В.; Пучкова, Г. В. (2020)

The purpose of the work is to study the chronic convulsive activity intensity in conditions of picrotoxin-induced kindling and due to recombinant antagonist of interleukin-1 receptors introduction as well as registration ...
Abnormalities in the GABAergic inhibitory system leading to the development of spike-wave discharges in the somatosensory cortex of WAG/Rij rats

Nejad, G. G.; Vastyanov, R. S.; Shahabi, P.; Alipoor, M. R.; Pakdel, F. G.; Неджад, Г. Г.; Васт’янов, Р. С.; Шахабі, П.; Аліпур, М. Р.; Пакдель, Ф. Г. (2015)

We investigated the effects of muscimol on generation of spike-wave discharges (SWDs) and short-term plasticity alterations in the somatosensory cortex of WAG/Rij rats. The rats were implanted with a twisted tripolar ...
Pathological morpho-functional dysintegration as the key pathogenetic mechanism of experimenatl liver cirrhosis

Vastyanov, R. S.; Dzygal, O. F.; Gorlitsyna, O. A.; Mykhailenko, V. L.; Lapshyn, D. Ye.; Nazarenko, o. Ya.; Вастьянов, Р. С.; Дзигал, О. Ф.; Горліцина, О. А.; Михайленко, В. Л.; Лапшин, Д. Є.; Назаренко, О. Я.; Вастьянов, Р. С.; Дзыгал, А. Ф.; Горлицына, А. А.; Михайленко, В. Л.; Лапшин, Д. Е.; Назаренко, О. Я. (2020)

The purpose of the study is to investigate the liver cirrhosis pathophysiological mechanisms in rats and to investigate the efficacy of pathogenetical correction of these pathology using L–arginine aspartate and tivortin. ...
The Experimental overactive bladder modeling

Iatsyna, O. I.; Vastyanov, R. S.; Savytska, I. M.; Vernygorodskyi, S. V. (2018)

An experimental study was conducted, which resulted in the development of a hyperactive urinary bladder model. Animals of the main group administered once daily for 14 days i.p. 0.3 ml of the hombiotensin, containing 0.45 ...
The experimental modelling of stress urinary incontinence

Iatsyna, O. I.; Vastyanov, R. S.; Savytska, I. M.; Vernygorodskyi, S. V. (2018)

The stress urinary incontinence (SUI), especially in women, constitutes most frequent complication of urogynecological diseases. Adequate and a stable reproducible model of SUI in white laboratory rats was created, using ...
Optimization of prediction of morphological disorders of skeletal muscles in experimental acute ischemia-reperfusion on the basis of combined changes in lipid peroxidation and antioxidant protection by neural network clustering

Selskyy, P. R.; Vastyanov, R. S.; Klishch, I. M.; Televiak, A. T.; Volska, A. S.; Kurylo, Kh. B.; Selskyy, B. P. (2020)

The paper proposes a method for optimizing the prediction of the development of morphological disorders of skeletal muscle in experimental acute ischemia-reperfusion based on combined changes in lipid peroxidation and ...
A comparative study on the effectiveness of application of different types of biological matrixes on mandibular alveolar mucosa lesion healing

Vyshnevska, H. O.; Kakabadze, Z. Sh.; Schnayder, S. A.; Zayats, L. M.; Tiron, O. I.; Vastyanov, R. S. (2020)

Periodontal diseases is one of the most relevant and important problem in modern dentistry due to their increasing prevalence in population, association with the occurrence of focus of chronic infection, progressive ...
The role of lipid peroxidation in the pathogenesis of experimental peritonitis

Savitsky, I. V.; Znamerovsky, S. G.; Dzygal, O. F.; Савицький, І. В.; Знамеровський, С. Г.; Дзигал, О. Ф. (2020)

In the first hour simulated fecal peritonitis development in the rats blood revealed an increase in the level of diene conjugates and malondialdehyde (p <0.001 compared with the results of intact animals. In second stage ...
Pathophysiological model of indirect revascularization in rats with microangiopathy of limbs caused by experimental streptozocin diabetes

Vastyanov, R. S.; Chekhlova, O. V.; Вастьянов, Р. С.; Чехлова, О. В.; Вастьянов, Р. С.; Чехлова, Е. В. (2019)

Despite the large number of publications, the model of experimental diabetes after the introduction of streptozotocin remains a subject of lively scientific debate. The purpose of this study was to develop a pathophysiological ...
Contribution of peroxide processes to pathogenetic mechanisms of experimental liver cirrhosis

Dzygal, A. F.; Grubnik, Yu. V.; Vastyanov, R. S. (2016)

The results of a series of experimental trials using rats with toxic liver cirrhosis are given. After 12 hours, and in 1, 3, 5 and 7 days after the pathological condition simulation, blood erythrocytes in animals as well ...
Research of effects by donators nitrogen of oxygen in complex therapy during experimental peritonitis

Savytskyi, І. V.; Tsypoviaz, S. V.; Lenik, R. G.; Bilash, О. V.; Zashchuk, R. H.; Miastkivska, I. V. (2019)

The research was conducted on 175 white rats of reproductive age (3 months), weight of animals – 180–220 g. Animals were divided into 4 groups: Group 1 – 20 intact animals. Group 2 – 50 rats with simulated fecal peritonitis. ...
Cytokines and Absence Seizures in a Genetic Rat Model

Luijtelaar, G.; Lyashenko, S.; Vastyanov, R.; Verbeek, G.; Oleinik, A.; Rijn, C.; Volokhova, G.; Shandra, A.; Coenen, A.; Godlevsky, L. (2012)

We investigated the role of two cytokines, IL-1β and TNF-α, in the development of absence seizures using a genetic model of absence epilepsy in WAG/Rij rats. We administered these cytokines to animals systemically and ...
The role of TNF-α in amygdala kindled rats

Shandra, A. A.; Godlevsky, L. S.; Vastyanov, R. S.; Oleinik, A. A.; Konovalenko, V. L.; Rapoport, E. N.; Korobka, N. N. (2002)

In the present study, the interaction between epileptogenesis and the immune system were studied in a kindling model. First, the effects of a single administration of TNF-α (5.0 µg/kg, i.p.) on seizure and EEG activity ...
Epidemiology and management of ovarian cancer based on the clinical experience of the southern region of Ukraine

Rybin, A.; Varabina, A.; Broshkov, M.; Рыбин, А. И.; Варабина, А. О.; Брошков, М. М. (2019)

The aim of the study was to evaluate the clinical and epidemiological characteristics of the contingent of patients with RH on the example of the southern region of Ukraine. The research was carried out at the clinical ...
Еndothelial dysfunction due to sodium nitrite

Savitsky, I. V.; Kryukovа, G. V.; Myastkivska, I. V.; Савицький, І. В.; Крюкова, Г. В.; М'ястківська, І. В.; Савицкий, И. В.; Крюков, Г. В.; Мястковская, И. В. (2020)

In the report of the World Health Organization from 1990 to 2016 to this day, Ukraine continues to occupy first place in the European region in morbidity and mortality from diseases of the cardiovascular system. One of the ...
Dynamics of vasoconstriction and vasodilation potential on the background of experimental rhegmatogenous retinal detachment and its correction

Savytskyi, I. V.; Levytskyi, I. M.; Levytska, G. V.; Miastkivska, I. V.; Kuzmenko, i. A. (2016)

Purpose: investigation of vasoconstriction and vasodilation potential in rhegmatogenous retinal detachment pathogenesis and analysis of correction methods effectiveness. It’s proven that endothelial dysfunction is an ...
HIV/AIDS statistical analysis and morbidity prediction among injection drug users in the Black Sea region of Ukraine

Talalaev, К. О.; Hodyak, V. S.; Vastyanov, R. S.; Todorova, A. V. (2019)

The development of methods for statistical analysis of large data volumes and availability of standard information processing packages to users shows signs of widespread their usage, including for medical forecasting. It ...

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