Integrative assessment of candidate gene polymorphisms distribution by forming a gene modification index in arterial hypertension with and without obesity: a new perspective in cardiology management

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dc.contributor.author Bondar, V. en
dc.contributor.author Chernyshova, K. en
dc.contributor.author Chernyshova, H. en
dc.contributor.author Kolomiiets, S. en
dc.contributor.author Klochko, V. en
dc.contributor.author Tbileli, V. en
dc.contributor.author Kryzhanovska, O. en
dc.contributor.author Dehtyar, Y. E. en
dc.contributor.author Krasiluk, N. en
dc.contributor.author Yershova, R. en
dc.contributor.author Bondar, K. en
dc.date.accessioned 2020-12-16T06:41:58Z
dc.date.available 2020-12-16T06:41:58Z
dc.date.issued 2020
dc.identifier.citation Integrative assessment of candidate gene polymorphisms distribution by forming a gene modification index in arterial hypertension with and without obesity: a new perspective in cardiology management / V. Bondar, K. Chernyshova, H. Chernyshova et al // European Heart Journal. 2020. Vol. 41, N 2. P. 2750. en
dc.identifier.uri https://repo.odmu.edu.ua:443/xmlui/handle/123456789/8435
dc.description.abstract The concept of evolutionary accumulation of candidate gene polymorphisms in the realization of the hypertensive phenotype becomes promising in understanding of arterial hypertension (AH). A large amount of data about genetic polymorphisms in population have been accumulated and perspective approaches to their integrative assessment are being formulated for practical management. The purpose of the research was to analyze and compare the proportion of modified candidate genes (CG) in the group of hypertensive patients with and without obesity with the group of non-hypertensive patients by calculating the gene modification index (GMI) for the assessment of possible usage of genetic stratification in the management of AH. en
dc.language.iso en en
dc.subject candidate gene polymorphisms distribution en
dc.subject gene modification index en
dc.subject arterial hypertension en
dc.subject obesity en
dc.title Integrative assessment of candidate gene polymorphisms distribution by forming a gene modification index in arterial hypertension with and without obesity: a new perspective in cardiology management en
dc.type Article en


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