Effect of the drug from soybean and avocado on the course of osteoarthrosis of the knee joints with concomitant metabolic syndrome in women in the menopausal period

Abstract

Te most common articular pathology is osteoarthrosis of the knee joints. More than 10 % of the world's population suffers from this disease. Te development of osteoarthrosis (OA) is also affected by metabolic syndrome (MS), which is characterized by abdominal obesity, dyslipidemia, arterial hypertension and disturbance of carbohydrate metabolism. Te combination of MS and osteoarthrosis creates conditions of overload for the functioning of axial joints, which is one of the main causes of premature disability and invalidization of the population. Treatment of OA of the knee joints in women in the menopausal period with concomitant metabolic syndrome presents great difculties. To achieve a stable result of treatment, therapy with chondroprotectors and nonsteroidal anti-inflammatory drugs (NSAIDs) is used. Treatment was carried out in 60 women in the menopausal period with MS, suffering from OA of knee joints. In the group of women in the menopausal period with OA of knee joints and MS who took therapy with the inclusion of the soybean and avocado drug alongside with NSAIDs, a signifcant effect was obtained with regard to arresting the pain syndrome, improving the quality of life, reducing the degree of inflammation as well as increased joint mobility compared with the group of patients, who took only chondroprotectors and NSAIDs.