Analgesic and anti-inflammatory activity of vanillin derivatives

dc.contributor.author	Boiko, Yu. A.	en
dc.contributor.author	Nesterkina, M. V.	en
dc.contributor.author	Shandra, A. A.	en
dc.contributor.author	Kravchenko, I. A.	en
dc.date.accessioned	2020-05-18T05:06:03Z
dc.date.available	2020-05-18T05:06:03Z
dc.date.issued	2019
dc.identifier.citation	Boiko Yu. A., Nesterkina M. V., Shandra A. A, Kravchenko I. A. Analgesic and anti-inflammatory activity of vanillin derivatives // Pharmaceutical Chemistry Journal. 2019. Vol. 53, N 7. P. 650–654.	en
dc.identifier.uri	https://repo.odmu.edu.ua:443/xmlui/handle/123456789/7130
dc.description.abstract	The analgesic activity of 4-hydroxy-3-methoxybenzaldehyde (vanillin) derivatives with different pharmacophore groups were studied in vivo in models of chemically induced pain induced by subplantar administration of the TRP ion channel agonists capsaicin and allylisothiocyanate. The anti-inflammatory actions of vanillin derivatives were demonstrated in a model of carrageenan-induced edema. The analgesic and anti-inflammatory activities of vanillin and its derivatives were studied; these are linked with the effects of these substances on TRPA1 and TRPV1 receptors.	en
dc.language.iso	en	en
dc.subject	Vanillin derivatives	en
dc.subject	TRPA1 and TRPV1 receptors	en
dc.subject	analgesic activity	en
dc.subject	anti-inflammatory activity	en
dc.title	Analgesic and anti-inflammatory activity of vanillin derivatives	en
dc.type	Article	en