Abstract:
Prognosis of cardiovascular risk (CVR) in patients with arterial hypertension (AH) is an important component of long-term management. The accumulated data of polymorphisms of candidate genes in AH form a reasonable prospect of using of genetic risk scores. The purposes of the research were to form a model of genetic stratification of CVR based on the evaluation of polymorphisms of candidate genes and calculation of gene modification index (GMI), to compare this model with existing scale SCORE and to evaluate the possibility of its use with prognostic purpose in patients with AH in Ukrainian population.
