The effectiveness of low-dose reserpine-containing phytodrugs in the treatment of arterial hypertension with metabolic syndrome in young patients

Abstract

The results of an open prospective clinical research on the use of low-dose reserpinecontaining phytodrugs in young patients with mild hypertension and concomitant metabolic syndrome are presented. 56 young patients with arterial hypertension of 1st degree and concomitant metabolic syndrome with low and moderate cardiovascular risk were examined, the age was from 18 to 43 years old, male/female ratio was 32/24. Analyzing the results of the research, a significant antihypertensive effectiveness was revealed as in reducing of daily average blood pressure, and of day/night blood pressure. Effective blood pressure control (˂130/80 mm Hg) was achieved in 75% patients. Additionally, the effect on carbohydrate and lipid metabolisms was assessed, and it was found the metabolic corrective action of low-dose reserpine-containing phytodrugs in young patients with mild hypertension and concomitant metabolic syndrome.