Synthesis and antioxidant and anti-influenza activity of aminomethanesulfonic acids

Khoma, R. E.; Gelmboldt, V. O.; Énnan, A. A.; Gridina, T. L.; Fedchuk, A. S.; Lozitsky, V. P.; Rakipov, I. M.; Vladyka, A. S.

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dc.contributor.author	Khoma, R. E.	en
dc.contributor.author	Gelmboldt, V. O.	en
dc.contributor.author	Énnan, A. A.	en
dc.contributor.author	Gridina, T. L.	en
dc.contributor.author	Fedchuk, A. S.	en
dc.contributor.author	Lozitsky, V. P.	en
dc.contributor.author	Rakipov, I. M.	en
dc.contributor.author	Vladyka, A. S.	en
dc.date.accessioned	2020-02-13T12:50:36Z
dc.date.available	2020-02-13T12:50:36Z
dc.date.issued	2019
dc.identifier.citation	Synthesis and antioxidant and anti-influenza activity of aminomethanesulfonic acids / R. E. Khoma, V. O. Gelmboldt, A. A. Énnan // Pharmaceutical Chemistry Journal. 2019. Vol. 53. N 5. P. 436–439.	en
dc.identifier.uri	https://repo.odmu.edu.ua:443/xmlui/handle/123456789/6466
dc.description.abstract	Aminomethanesulfonic acid (I) and its N-methyl- (II), N-(2-hydroxy)ethyl- (III), N-(tert-butyl)- (IV), N-benzyl- (V), and 4-(N-phenylaminomethyl)phenyl- (VI) derivatives (V and VI not previously reported) were synthesized and characterized by elemental analysis and IR and mass spectroscopy. The in vitro antioxidant activities of aminomethanesulfonic acids I-VI were found to be comparatively weak. Compounds IV and V suppressed statistically significantly reproduction of influenza virus strains A/Hong Kong/1/68 (H3N2) and A/PR/8/34 (H1N1) in chorioallantoic membrane tissue culture.	en
dc.language.iso	en	en
dc.subject	aminomethanesulfonic acids	en
dc.subject	antioxidant activity	en
dc.subject	anti-influenza activity	en
dc.subject	A/Hong Kong/1/68 (H3N2)	en
dc.subject	A/PR/8/34 (H1N1)	en
dc.title	Synthesis and antioxidant and anti-influenza activity of aminomethanesulfonic acids	en
dc.type	Article	en