Definition of efficiency of different approaches in treatment of infertility for patients with polycystic ovary syndrome and hyperprolactinemia

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women. The clinical manifestation of PCOS varies from a mild menstrual disorder to severe disturbance of reproductive and metabolic functions with severe long-term health consequences. High-frequency of endocrine-metabolic disorder’s and anovulatory infertility and also frequent absence of effect from the use of traditional charts of medicament induction of ovulation resulted in the search of alternative ways of proceeding in fecundity. The aim of this study was to evaluate the clinical efficiency of different treatments cancellation and infertility in women with PCOS and hyperprolactinemia. We performed retrospective analysis of 502 consecutive case histories during 5 years of reproductive results of treatment of women is with anovulatory infertility, caused by different factors. Aim of the study was to determine the efficiency of conservative and surgical treatment. Differentiated application of conservative medical therapy allows to attain the effect of proceeding in a fertile function in 33, 8% of patients. It is found that surgical induction of ovulation by ovarian laparoscopic partial degradation is an option in the management of female infertility associated with PCOS, especially as a second-line treatment after the failure of clomiphene citrate treatment, enhancing the efficiency of complex infertility treatment to 40%. It is feasible to develop an algorithm differentiated use of infertility treatments in women with PCOS and hyperprolactinemia.