Abstract:
The article presents our experience of advanced gynecological malignancies surgical
treatment. We retrospectively analyzed 1215 cases of gynecological malignancies and selected 313 patients
with locally advanced disease. All patients undergone surgical treatment in University Clinic of Odessa
national medical university from 2006 till 2017. 32 HIPEC procedures were included in this study, 24 with
cytoreduction. One-year survival was 88,6 % for cervical cancer, 85,2 % for ovarian cancer, 79,1 % for
endometrial cancer. Five and ten year survival rate was 31 % and 14 % among ovarian cancer patients,
18 % and 9 % for ovarian cancer, 38 % and 18 % for endometrial cancer respectively. Cytoreduction with
HIPEC were well tolerated with no perioperative mortality.
