Мета дослідження – вивчення особливостей впливу комбінованої ліпідокоригувальної терапії на показники психічного здоров’я ЯЖ у хворих на стабільну стенокардію.
According to current recommendations, lipid-lowering therapy is considered as base
for treatment of atherosclerosis. Statins are recognized leaders in lipid-lowering effects, however their
impact on high-density lipoproteins is insignificant. Fibrates, on the contrary, have a more positive
impact on this factor, as well as on triglycerides, for which reason it seems reasonable to use a combination
of statins and fibrates. This combination is rarely used in medical practice though for fear of
increased side effects and reduced quality of life in the patients.
The research objective — is to study the impact of the combination lipid-lowering therapy on
mental health indicators of the quality of life in patients with stable angina pectoris.
Мaterials and methods. The study involved 64 patients with stable angina, mean age (58.52±
±1.53) years. Group I (n=32) received a standard set of medications for patients with stable angina
acompanied by atorvastatin 20 mg daily; group ІІ received atorvastatin in a reduced dose of 10 mg
per day and fenofibrate in a dose of 145 mg per day. The patients subjectively assessed their condition
using the MOS SF-36 questionnaire.
