Результаты проведенных исследований свидетельствуют, что при физиологической беременности равновесие регуляторных процессов кардиоритма определялось у 86,6 % матерей и 90,4 % плодов. При плацентарной дисфункции у беременных в регуляции кардиоритма выявлено напряжение симпатических (сегментарных) структур в 32,9 % (против 11,3 %) случаев и/или автономных — в 49,4 % (против 2,3 %), а у плода преобладали автономные регуляторные влияния в 30,6 % (против 2,2 %), с реализацией регуляторно-адаптационных реакций только в компенсированную и субкомпенсированную фазы плацентарной дисфункции. Полученные результаты необходимо использовать при разработке алгоритма диагностических и прогностических мероприятий у женщин с факторами риска.
The functional estimation of mother-placenta-fetus system represents an important problem in obstetrics. Possibility of many diagnostic methods application in obstetrical practice, for the natural reasons, is limited. The universal indicator of compensatory-adaptive reactions is cardiovascular system which reflects the organism condition regulation mechanisms and adaptive possibilities. A research objective — to study comparative aspects of mother’s, fetus and newborn cardiac rhythm regulation characteristics at physiological pregnancy and placental dysfunction on the basis of the cardiac rhythm variability estimation. 220 pregnant women and their fetuses were under observation (85 — main group with different grades of placental dysfunction and 135 — control group) to perform clinical obstetrical examination, ultrasonic feto- and placentometry, uterine-placental-fetal Doppler, Electrocardiotocography analysis, ELISA for mothers’ and newborns’ hormonal serum levels. We used cardiac
rhythm variability, spectral, mathematic and non-parametric analysis for the pregnant, fetus and newborn
regulatory and adaptative processes state diagnostics. The results of the research testify that at physiological pregnancy balance regulation processes of cardiac rhythm was defined in 86.6% of mothers and in 90.4% of fetuses. At placental dysfunction in pregnant women in cardiac rhythm regulation the tension of sympathetic
(segmentary) structures in 32.9% (against 11.3%) and/or autonomous — in 49.4% (against 2.3%)
was revealed, and at fetus the autonomous regulation influences in 30.6% (against 2.2%) were prevailed,
with regulatory and adaptive reactions realization only in the compensated and sub-compensated
placental dysfunction phases. The received results are necessary for the diagnostic and forecasting
actions’ algorithm workout in women with risk factors.
