Catecholaminergic neurotransmission activity modulation determines emotional changes in rats with chronic unpredictable stress

Abstract

The emotional component of the stressful nature of our lives is constant, varied in expression and in the nature of emotions. The emotional background often becomes the leading factor determining the severity of stress. We were interested in the peculiarities of catecholaminergic neurotransmitter systems functioning whose activity modulation in conditions of chronic unpredictable stress can significantly change the nature of animals’ emotional reactions. Aim. To study the influence of serotonergic, dopaminergic and adrenergic neurotransmitter systems functional activity modulation on the emotional behavior expression in rats in chronic unpredictable stress.