Abstract:
The data represented here are in relation to the manuscript
(Godlevsky et al., 2025) [1], which quantitatively estimated
the effects of the lateral cerebellar nucleus (LCN) electrical
stimulation (100 Hz) in rats kindled with pentylenetetrazol
(PTZ) daily administration. Both behavioral Racine scale scoring seizure severity and EEG seizure discharges registered in
the frontal cortex of rats kindled to the early stage of kindling (not exceeded 2 scored seizure severity) after 9-11 PTZ,
and fully developed kindling (4-5 scored seizure severity) after 21 PTZ were quantitatively analyzed. The data in the Tables favors the contribution of LCN to the dynamic of behavioral and EEG seizures, namely, the facilitation of myoclonic
seizures at an early stage and the prevention of generalized
seizures at the stage of kindled tonic-clonic seizures. Accordingly, all results are presented in primary individual form and
quantitatively analyzed, which might better understand LCN’s
role in the pathogenesis of chronic epileptic syndrome.
