Fluorescent border diagnosis and surgical treatment of the malignant process of external nose skin.

Abstract

OBJECTIVE. The purpose of the study was to find out the diagnostic value of the Photolon® as a fluorescent visualization of the borders of malignant lesions of the external nose, with the aim of radical surgical removal of the tumor. MATERIAL AND METHODS. During the period from 2016 until 2018, 30 patients with malignant neoplasms of the external nose were examined and operated on in the Otolaryngology-Head and Neck Department. During the study, patients underwent surgical removal of tumors by using a complex of anemic Klein's solution and fluorescent imaging of the lesion in 15 patients, while 15 patients were operated on without using Klein’s solution and fluorescent imaging. RESULTS. Observation in the postoperative period showed that, in the group of patients who underwent fluorescent imaging with adding anemic Klein's solution, the postoperative period was satisfactory, and no signs of recurrence were observed. In the group operated on without fluorescent imaging and without conducting anemic Klein's solution, after two years 4 (26.6%) patients were diagnosed with a superficial recurrence of skin cancer at the border of the cartilage and bone. CONCLUSION. The authors provide suggestions for the effectiveness of the use of a complex of fluorescent imaging of the border of the tumor lesion and prophylactic anemic solution in the surgical removal of the tumor of the outer nose.