Abstract:
The functional results of the
radical prostatectomy (RPE) in locally advanced
prostate cancer (PCa) are worse because the nerve
sparing technique do not use. The stricture of the
vesicourethral anastomosis is detected in 7.5 - 14%
cases (Wang R. et al, 2012), about 17% patients have
incontinence after surgery in pT3 prostate cancer.
The trophic decoders result in scars surround of
the vesicourethral anastomosis that might be one of
cause of the incontinence. Regenerative technology
such as platelet rich plasma (PRP) can improve
the trophic properties of the tissue.
Objective. The aim was to study the influence
of the PRP injections on morphological changers
of the urethral anastomosis on an experimental
animal model. Then the first experience of the
intraoperative PRP injection in vesicourethral
anastomosis area during RPE in pT3a-pT3b PCa
was assessed.
