Abstract:
he aim: To analyze the state of periodontal tissues against the background of Helicobacter pylori invasion in dynamics and to propose a possible mechanism
of development of in%ammatory periodontal diseases in patients with Helicobacter pylori-associated pathology of the gastrointestinal tract.
Materials and methods: We examined 43 patients with Helicobacter pylori-associated gastrointestinal pathology and 42 patients of the same age without
somatic pathology, including without gastrointestinal pathology associated with Helicobacter pylori. Clinical and laboratory research methods (clinical, instrumental, biochemical, histological methods) were used.
Results: Comparing the data of clinical observations and the results of laboratory studies of patients with in%ammatory periodontal disease on the background
of Helicobacter pylori-associated gastrointestinal pathology, obtained in di&erent observation periods, we can assume that basic dental treatment of periodontal
disease in such patients undergoing eradication therapy does not provide stable anti-in%ammatory, antimicrobial and antioxidant e&ect, which leads to reduced
periods of remission and recurrence of periodontal disease, where oral dysbiosis plays a crucial role.
Conclusions: Comparing the data of clinical observations and the results of laboratory studies of patients with chronic gingivitis on the background of Helicobacter
pylori-associated gastrointestinal pathology, obtained in di&erent observation periods, we can say that they correlate with each other and suggest that the
basic dental treatment of chronic gingivatis on the background of H.pylori-associated pathology of the gastrointestinal tract, which is currently undergoing
a course of eradication, does not give a stable anti-in%ammatory, antimicrobial and antioxidant e&ect, which leads to recurrence of periodontal disease and
shortening remission periods, where oral dysbiosis plays a crucial role.
