Abstract:
Among the factors that can influence the course and effectiveness of
the treatment of pulmonary tuberculosis (TB) the genetic characteristics of
patients play an important role. It is established that cytochrome (CYP)
3A4/5 is involved in metabolism of more than 30 % of xenobiotics.
Consequently, the activity of this enzyme is greatly influenced by responsible
genes, such as CYP3А4.
