Короткий опис (реферат):
The histological diagnosis of neurogenic tumors remains a challenge,
which may be indicated particularly by the fact that new entities appeared in the new
edition of the World Health organization (WHO) classification.
Purpose: To review the histomorphologic and immunohistochemic features of rare
variants of neurogenic ocular (retinal) tumors in adults.
Material and Methods: Six rare ocular tumors were selected for the study from all
clinical material submitted for pathohistological examination from 2017 to 2020 based
on the presence of morphological evidence of neurogenic differentiation.
Results: The study sample of six rare neurogenic retinal tumors in adults was
conventionally divided into three types: (1) retinal tumors immunohistochemically
similar to cellular ependymoma, but histologically similar to retinoblastoma;
(2) tumors showing no histological pattern characteristic for dictyoma, but the
immunohistochemical features of neuroepithelial differentiation; and (3) tumors showing
histological patterns similar to medulloepithelioma, but the immunohistochemical
features of glial markers.
Conclusion: Obviously, when dividing these tumors into histogenetic groups, not only
the histological structure and immunohistochemical profile, but also tumor location
and typical patient age should be taken into account.
