Abstract:
The article presents the experimental results of the investigation the glutathione
system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian
ascites tumor. In the experimental carcinogenesis of the ovaries, the activity of glutathione
reductase and glutathione peroxidase was inhibited at all intervals of the study during longterm observation. After the presence of carcinogenesis in the body, the number of reactions
that do not lead to complete utilization of metabolites. Glutathione reductase activity
increases between 4 and 6 months. And the activation of glutathione peroxidase for the entire
period only decreases. The experiment showed that gammaglobulin with long-term treatment
can increase the activity of the glutathione system.
