Особливості мікросудинної мережи маткових перегородок у жінок з септатною маткою та репродуктивними порушеннями

Abstract

The purpose: to study the features of the microvascular network of metroplastic samples of septa from women with septate uteri and reproductive disorders. Materila and methods: 64 women of reproductive age with septate uterus underwent hysteroresectoscopy, metroplasty, immunohistochemical study of the microvascular network of metroplastic septal samples. CD34 was determined. As a morphological control, 10 samples of uterine floor tissue were taken hysterectomically from the women under examination because of cervical cancer. The total vascular area / field of view in the septa of the uterus was (10 247,82 ± 95,94) μm2, while in the control - (12 155,79 ± 347,32) μm2 (p<0,01), which corresponded to the percentage area of the vessel (5.44 ± 0.05) % and (6.43 ± 0.18) %, respectively (p<0.01). The value of the F-circle (irregularity of microvessels) in the group with septal uteri was (0.629 ± 0.006) compared with (0.637 ± 0.017) for the control group (p<0.05). In addition, comparison of the value of the F-shape (deformation of microvessels) between the group with uterine septa and the control group also revealed a statistically significant difference - (0.532 ± 0.005) against (0.569 ± 0.016 (p<0.04)). Conclusion. The area of blood vessels of the uterine septum is significantly smaller than in a normal uterus, and their abnormal morphology is observed.