Короткий опис (реферат):
Bronchial asthma (BA) is a multifactorial disease which develops under the influence
environmental factors in the presence of individual’s genetic predisposition. The mechanisms
associated with the respiratory system dominate in its pathogenesis. The objective: to
determine the regulatory features of the uncontrolled course of asthma. The results obtained.
At the outpatient stage of treatment 71 male and female patients, mean age 41.0 ± 0.8 have
been examined with the use of spiroarteriocardiorhythmography (SACRG). The patients
under examination were divided into 2 groups: the group of comparison (n = 20), and the
main one (n = 51). Alfa - coefficient in high (BRHF) and low (BRLF) frequencies,
hemodynamic and minute volume of blood circulation (HMV, l), indexes of cardiovascular
and respiratory systems synchronization and parameters of the cardiovascular system in
patients with asthma were determined. Conclusions. In BA at the background of total
respiratory capacity significant increase and growth of neurohumoral regulatory influences
there is a significant decrease of the sympathetic link activity in the regulation of uncontrolled
respiration and relative reduction of the volume velocity of inspiration, which should be taken
into account when determining the severity of asthma.
