• The effect of dietary fat supplements on the activity of palmitic and stearic acid desaturases based on the results of a study of the fatty acid composition of neutral lipids in blood serumand liver of rats receiving a fat-free diet 

  Levitsky, A. P.; Gozhenko, A. I.; Velichko, V. V.; Selivanskaya, I. A. (2022)

  Desaturase enzymes are involved in the formation of monoenoic acids from saturated fatty acids. One such enzyme is stearyl-CoA-desaturase (SCD1), which converts stearic acid to oleic acid. The aim of ...
• Therapeutic and preventive effectiveness of antidisbiotic agents in rats with lipid intoxication 

  Levitsky, A. P.; Gozhenko, A. I.; Velichko, V. V.; Selivanskaya, I. A.; Markov, A. V. (2021)

  Aim: to determine the effect of antidisbiotic agents on the state of the organism of rats under conditions of lipid intoxication and to propose a comprehensive method for assessing therapeutic and prophylactic efficacy. ...
• Therapeutic and prophylactic efficiency of polyfunctional anti-disbiotic drugs under conditions of experimental lipid intoxication 

  Levitsky, A. P.; Gozhenko, A. I.; Selivanskaya, I. A.; Lapinskaya, A. P.; Tomilina, T. V.; Badiuk, N. S. (2021)

  Aim: to compare the therapeutic and prophylactic efficiency (TPE) of four polyfunctional antidisbiotic drugs (PFAD) in experimental lipid intoxication. Methods: TPE was assessed by the nature of changes in blood serum ...
• Influence of fat-free, fat and sucrose diets on the indicators of lipid metabolism in rats 

  Levitsky, A. P.; Selivanskaya, I. A.; Lapinskaya, A. P.; Pupin, T. I.; Badiuk, N. S. (2021)

  The aim. To determine the effect on lipid metabolism in the serum of rats of diets: fat-free, fat and sucrose. Materials and methods. Feeding experiments were carried out on rats divided into 3 groups: the first received ...
• Influence of high-fat nutrition with different fat-acid composition of fats on lipid peroxidation processes in rat's organs and tissues 

  Levitsky, A. P.; Egorov, B. V.; Gozhenko, A. I.; Badiuk, N. S.; Selivanskaya, I. A.; Lapinskaya, A. P. (2021)

  The aim. To determine the effect of high-fat diet (HFD) using fats of different fatty acid composition on the content of malondialdehyde (MDA) in the organs and tissues of rats and on catalase activity. Materials and ...
• Efficiency of ademethionine in oxidative stress in tissues of irradiated rats 

  Stepanov, G. F.; Tereshchenko, L. O.; Oleinik, E. V.; Maryniuk, G. S.; Budalenko, O. I.; Dubna, E. S. (2021)

  Introduction. Ionizing radiation in low doses of low intensity causes prolonged activationof lipid per oxidation and depletion of the antioxidant system in a living organism. Moreover, Ademethionine is currently being ...
• Simplex representation of molecular structure as universal QSAR/QSPR tool.  

  Kuz’min, V.; Artemenko, A.; Ognichenko, L.; Hromov, A.; Kosinskaya, A.; Stelmakh, S.; Sessions, Z. L.; Muratov, E. N. (2021)

  We review the development and application of the Simplex approach for the solution of various QSAR/QSPR problems. The general concept of the simplex method and its varieties are described. The advantages of utilizing this ...
• Effect of Total Extract of Milk Thistle Fruits on the Absorption of Glycine in the Rats Small Intestine under Physiological Conditions 

  Storchylo, O. V. (2015)

  Objectives and method: To determine the effect of total extract of milk thistle fruits on the velocity of glycine absorption in the chronic experiments under physiological condition with no operation trauma, pain, narcosis ...
• Biochemical indicators of the organism condition of rats which received high-fat diets with different fatty acid composition 

  Levitsky, A. P.; Selivanskaya, I. A.; Selivanskaya, A. V.; Pupin, T. I. (2020)

  Aim. To determine the effects on the body of high-fat diets (HFD) with different fatty acid composition. Methods. Used ordinary sunflower, olive, palm and butter, which were introduced into the feed in an amount of 15 ...
• Therapeutic and preventive effectiveness of oral application of phitogels “Kvertulin”, “Biotrit” and “Dubovy” in inflammatory complications in the digestive system of rats treated with thermoperoxide sunflower oil 

  Levitsky, A. P.; Markov, A. V.; Pupin, T. I.; Labush, Iu. Z.; Selivanskaya, I. A.; Lapinskaya, A. P. (2021)

  Aim. It has been established that the consumption of thermoperoxide fats causes the development of pathological processes in the tissues of the mouth, stomach, intestines and liver. The purpose of this work is to determine ...
• Comparative nephroprotective efficiency of polyfunctional mucous-adhesive phytogels 

  Gozhenko, A. I.; Levitsky, A. P.; Stepan, V. T.; Selivanskaya, I. A.; Pustovoit, I. P. (2021)

  Aim. To compare the nephroprotective effect of oral applications of different phytogels in experimental kidney pathology. Methods. We used phytogels: "Kvertulin" (quercetin + inulin + calcium citrate), "Biotrit" (juice ...
• Comparative effect of different pathogens on the condition of dysbiosis in rat kidneys 

  Levitsky, A. P.; Selivanskaya, I. A.; Stepan, V. T.; Pustovoit, P. I.; Stepan, B. T.; Stepan, N. A. (2020)

  Aim. Compare the effect of different pathogens on the development of kidney dysbiosis. Methods. The pathogens used were hydrazine sulfate, prednisolone, cyclophosphamide, lincomycin, and lipopolysaccharide (LPS). The ...
• Effect of fat diet on essential fatty acid metabolism of neutral lipids in rat blood serum 

  Levitsky, A. P.; Khodakov, I. V.; Pupin, T. I.; Markov, A. V.; Selivanskaya, I. A. (2021)

  Aim. To determine the effect of dietary fats on the content and metabolism of polyunsaturated fatty acids (PUFA) in the fraction of neutral lipids blood serum. Methods. The effect of sunflower, high oleic sunflower (HOSO) ...
• Effect of the new dental elixir on the condition of rats’ periodontal tissues with simulated metabolic syndrome 

  Kravchenko, L. S.; Appelhans, O. L.; Polyakov, A. Ye.; Pasechnik, O. V.; Shcherbakov, S. V.; Кравченко, Л. С.; Аппельханс, О. Л.; Поляков, А. Є.; Пасечник, О. В.; Щербаков, С. В. (2020)

  Biochemical changes in the blood serum, liver and gingival tissue were examined during simulation of the metabolic syndrome of alimentary genesis in experiment on 28 white male rats of reproductive age with an average ...
• Water Flow from Different Solutions During Perfusion of the Functioning Portion of the Small Intestine of the Rats In vivo 

  Storchilo, O. V. (2017)

  Thanks to the use of nuclear energy a society lives under the conditions of increased radiation background. Malformations and other inherited diseases caused by damage to the genetic apparatus by low doses of irradiation appear ...
• Analysis of the Role of Satiety of the Parents during Irradiation in the Assimilation of Substrates of the Protein Origin in two Generations of their Posterity 

  Storchilo, A. V. (2016)

  Thanks to the use of nuclear energy a society lives under the conditions of increased radiation background. Malformations and other inherited diseases caused by damage to the genetic apparatus by low doses of irradiation appear ...
• Absorption of Glycine in the Small Intestine of Rats Under Physiological Condition 

  Storchilo, O. V. (2015)

  Objectives and method: To determine the velocity of glycine absorption in the chronic experiments under physiological condition with no operation trauma, pain, narcosis and atrophy of the small intestine using and ...
• Membrane digestion and absorption of some nutrients in vitro and in vivo: Revision and analysis of own Data 

  Storchylo, O. V. (2018)

  The results of investigations of digestion and absorption of carbohydrates (glucose and maltose) in vitro by the preparations of accumulating mucous and in vivo in the chronic experiments on isolated and functioning ...
• Perfusion of the Functioning Portion of the Small Intestine of the Rats: Parameters of Perfusion and Dependence of the Velocity of Absorption of Glucose on the Velocity of Perfusion 

  Storchylo, O. V. (2017)

  Objectives and method: To research the parameters of perfusion of the functioning portion of the rats′ small intestine in the chronic experiments under physiological condition without operation trauma, pain, narcosis ...
• Role of bile in adequacy of the data of experiments on the small intestine of rats in vitro and in vivo 

  Storchylo, O. V. (2018)

  Studies of the functions of the Small Intestine in the experiment occur on model systems in conditions in vitro, in situ, and in vivo. The creation of model conditions presupposes the presence of limitations on certain ...

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