Оptimisation of medicines provision for women with obesity in menopause: Qualification work for the educational qualification “Master” in specialty 226 “Pharmacy, industrial pharmacy”

Abstract

The research is devoted to the problem of obesity in postmenopausal women, the analysis of current treatment approaches, and the role of pharmaceutical care in optimizing therapy. Obesity is a chronic multifactorial disease characterized by excessive accumulation of adipose tissue and is associated with the development of metabolic syndrome, diabetes mellitus, cardiovascular diseases, and certain types of cancer. In postmenopausal women, the risk of obesity significantly increases due to hormonal changes leading to metabolic disturbances and weight gain. The study analyzes current clinical guidelines for the treatment of obesity, including therapeutic and surgical approaches. The therapeutic approach involves lifestyle modification, diet therapy, increased physical activity, behavioral therapy, and pharmacotherapy, which is indicated for patients with a body mass index (BMI) ≥30 kg/m2 or ≥27 kg/m2 in the presence of obesity-related complications. Surgical treatment is applied in cases where conservative therapy is ineffective. It is emphasized that effective obesity management requires a comprehensive and interdisciplinary approach.